| Yazarlar |
Doç. Dr. Emin KARAKURT
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Nüvit COŞKUN
Kafkas Üniversitesi, Türkiye |
Prof. Dr. Serpil DAĞ
Kafkas Üniversitesi, Türkiye |
Prof. Dr. Enver BEYTUT
Kafkas Üniversitesi, Türkiye |
Veysel Soydal Ataseven
Hatay Mustafa Kemal Üniversitesi, Türkiye |
Prof. Dr. Volkan YILMAZ
Kafkas Üniversitesi, Türkiye |
|
Fırat Doğan
Hatay Mustafa Kemal Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Hilmi NUHOĞLU
Kafkas Üniversitesi, Türkiye |
Prof. Dr. Celal Şahin ERMUTLU
Kafkas Üniversitesi, Türkiye |
Doç. Dr. Uğur AYDIN
Türkiye |
Doç. Dr. Mushap KURU
Kafkas Üniversitesi, Türkiye |
Arş. Gör. Ayfer YILDIZ UYSAL
Kafkas Üniversitesi, Türkiye |
| Özet |
| Papilloma and fibropapilloma cases are quite common in cattle breeding, which cause economic losses due to decrease in the production of milk, meat, and also impair the quality of hide. In this study, we aimed to determine viral etiology and investigate p53 expression levels with immunohistochemical methods from a total of 30 cases. The study material was collected between 2013 and 2021 in Kars, Turkey. Paraffin embedded tissues were used for earlier cases in which the freshly specimens could not be provided. Cases were investigated for papillomavirus etiology with polymerase chain reaction (PCR) using FAP59/FAP64 and MY09/MY11 primer pairs. In 20 of the 30 cases papillomaviruses were identified, and 10 cases were identified as Bovine papillomavirus-1 (BPV-1), 1 case as BPV-2, 1 case as BPV-12, and 1 case as equus caballus papillomavirus 2 (EcPV-2) after sequence analysis. p53 immunostaining was also performed, and the cases were graded according to the positively stained cells. In conclusion BPV-12 was detected for the first time in our country, EcPV-2 was detected first time in cattle indicating cross species infection and p53 was staining most evident in BPV-1 and BPV-2 cases and BPV-12 and EcPV-2 was not stained. |
| Anahtar Kelimeler |
| Cattle,Immunohistochemistry,Papilloma,Polymerase chain reaction,p53 |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Archives of Microbiology |
| Dergi ISSN | 0302-8933 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | Türkçe |
| Basım Tarihi | 01-2022 |
| Cilt No | 204 |
| Doi Numarası | 10.1007/s00203-022-02902-0 |
| Makale Linki | http://dx.doi.org/10.1007/s00203-022-02902-0 |
| Atıf Sayıları | |
| WoS | 2 |
