| Yazarlar |
Nevin İlhan
Fırat Üniversitesi, Türkiye |
|
Hilal Güngör
Türkiye |
Doç. Dr. Hüseyin Fatih GÜL
Kafkas Üniversitesi, Türkiye |
|
Hatice Eröksüz
Fırat Üniversitesi, Türkiye |
| Özet |
| Endoglin (CD105) is a receptor for the transforming growth factor-beta 1 (TGFβ1) with crucial role in vascular development and angiogenesis. Additionally, vascular endothelial growth factor (VEGF) overexpression has been associated with advanced stage and poor survival for several cancer types. These molecules have been shown to be useful markers for identifying proliferating endothelium involved in tumor angiogenesis, especially in patients with cancer at risk of developing metastases. The aim of this study was to evaluate the relationship between VEGF and endoglin expression in an experimental model of colorectal cancer, as well as to investigate the effect of cyclooxygenase-2 (COX2) inhibitors on tumor development incidence. |
| Anahtar Kelimeler |
| Colorectal cancer,angiogenesis,endoglin,VEGF,COX-2 inhibitors |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | ANTICANCER RESEARCH |
| Dergi ISSN | 0250-7005 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 08-2016 |
| Cilt No | 36 |
| Sayı | 8 |
| Sayfalar | 3953 / 3959 |
