| Yazarlar |
Bülent Özlek
Türkiye |
|
Eda Özlek
Türkiye |
|
Ağuş Hicaz Zencirkıran
Türkiye |
|
Mehmet Tekinalp
Türkiye |
|
Serkan Kahraman
İstanbul Rumeli Üniversitesi, Türkiye |
|
Oğuzhan Çelik
Türkiye |
|
Cem Çil
Türkiye |
|
Özcan Başaran
Türkiye |
|
Volkan Doğan
Muğla Sıtkı Koçman Üniversitesi, Türkiye |
|
Bedri Caner Kaya
Sağlık Bilimleri Üniversitesi, Türkiye |
İbrahim RENCÜZOĞULLARI
Kafkas Üniversitesi, Türkiye |
|
Ösken Altuğ
Türkiye |
|
Lütfü Bekar
Hitit Üniversitesi, Türkiye |
|
Mustafa Ozan Çakır
Zonguldak Bülent Ecevit Üniversitesi, Türkiye |
|
Yunus Çelik
Türkiye |
|
Kadir Uğur Mert
Eskişehir Osmangazi Üniversitesi, Türkiye |
|
Kadriye Memiç Sancar
Türkiye |
|
Samet Sevinç
Türkiye |
|
Gurbet Özge Mert
Türkiye |
|
Murat Biteker
Muğla Sıtkı Koçman Üniversitesi, Türkiye |
| Özet |
| Background: Clinical characteristics of patients with heart failure may vary geographically. However, limited data are available regarding the geographical differences of patients with heart failure and preserved ejection fraction.Aims: The present subgroup analysis aims to investigate the geographical differences in clinical characteristics, management, and primary etiology of patients with heart failure and preserved ejection fraction in Turkey.Study Design: A cross-sectional study.Methods: A comPrehensive, ObservationaL registry of heart faiLure with mid-range and preserved ejection fractiON (APOLLON) is a multicenter and observational study conducted in seven regions of Turkey (NCT03026114). The present study is a post-hoc analysis of the APOLLON registry. In this substudy, we compared the clinical characteristics of 819 consecutive patients with heart failure and preserved ejection fraction (mean age, 67 years; 57.8% women) admitted to cardiology outpatient units in different geographical regions.Results: Based on the geographical distribution of the entire Turkish population, the highest number of patients enrolled were from Marmara (271 patients, 33.1%). All demographical characteristics, clinical and laboratory findings, comorbidities, primary etiology, and medications prescribed were significantly different between the regions. Furthermore, inter-regional gender differences were identified. Comparatively, the Aegean and Mediterranean regions had older patients with heart failure and preserved ejection fraction (p<0.001), and the Black Sea, Southeast, and East Anatolia regions had predominantly male patients (51.2, 54.5, and 56.9%, respectively; p=0.002). Notably, the Mediterranean and Southeast Anatolia had more symptomatic patients, and history of hospitalization for heart failure was more prevalent in Southeast Anatolia (33.3%, p<0.001). Prevalence of atrial fibrillation was higher in the Mediterranean and Southeast Anatolia regions (51 and 48.5%, p<0.001), and patients with heart failure and preserved ejection fraction had a higher prevalence of hypertension in the Mediterranean, Southeast Anatolia, and Black Sea regions (p=0.002). Angiotensin-converting enzyme inhibitors were more frequently prescribed in East Anatolia (52.3%, p=0.001), and the prevalence of patients with heart failure and preserved ejection fraction using loop diuretics (48.8%, p=0.003) was higher in the Black Sea region.Conclusion: This study was the first to show geographical differences in clinical characteristics of patients with heart failure and preserved ejection fraction in Turkey. Determination of the clinical characteristics of the heart failure and preserved ejection fraction population based on the geographical region may enables physicians to adopt a region-specific clinical approach toward heart failure and preserved ejection fraction. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Balkan Medical Journal |
| Dergi ISSN | 2146-3123 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 07-2019 |
| Cilt No | 36 |
| Sayı | 4 |
| Sayfalar | 235 / 244 |
| Doi Numarası | 10.4274/balkanmedj.galenos.2019.2019.2.17 |
| Makale Linki | http://www.balkanmedicaljournal.org/pdf.php?id=2089 |
| Atıf Sayıları |
