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Evaluation of Systemic Endothelial Dysfunction in Retinal Vein Occlusions.   
Yazarlar
Erdinç Bozkurt
Türkiye
Türkhun Çetin
Türkiye
 İbrahim RENCÜZOĞULLARI İbrahim RENCÜZOĞULLARI
Kafkas Üniversitesi, Türkiye
Özet
Objectives: Our aim in this study was to evaluate the systemic endothelial dysfunction status and carotid intima-media thickness (CIMT) in patients with retinal vein occlusion (RVO). Methods: Seventy-six patients who presented to the clinic with the diagnosis of RVO and 76 age- and gender-matched healthy individuals without a RVO history were included in the study. The patients’ best-corrected visual acuity (BCVA) and central macular thickness (CMT) were measures, and diabetes, hypertension, hyperlipidemia, carotid artery disease, body mass index, and smoking histories were recorded. The endothelial function levels of the patients, pulse wave velocity (PWV), flow-mediated dilation (FMD), and CIMT were measured. Endothelial dysfunction was detected by applying the FMD technique to the brachial artery. CIMT was evaluated by B-mode ultrasonography. Serum hematological parameters were evaluated. Results: BCVA (logMAR) was 1.39±1.30 in patients with RVO and 0.028±1.22 in the control group (p<0.001). CMT was 588.76±104.02 μm in patients with RVO and 265.20±45.11 μm in the control group (p=0.001). Hypertension, diabetes, and hyperlipidemia were found to be significantly higher in patients with RVO (p-value 0.001, 0.002, and 0.001, respectively). There was a significant difference between the groups in terms of FMD, PWV, and CIMT (all of them, p<0.001). Conclusion: The deterioration of FMD and PWV, which are indicators of endothelial dysfunction in patients with RVO, suggests that systemic endothelial dysfunction may play a role in the pathogenesis of RVO. Comprehensive studies with more patient participation are needed.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü Uluslararası alan indekslerindeki dergilerde yayımlanan tam makale
Dergi Adı Beyoglu Eye Journal
Dergi ISSN 2459-1777
Dergi Tarandığı Indeksler EBSCO, PUBMED
Makale Dili Türkçe
Basım Tarihi 01-2022
Cilt No 7
Sayı 2
Sayfalar 126 / 133
Doi Numarası 10.14744/bej.2022.44265
Makale Linki http://dx.doi.org/10.14744/bej.2022.44265
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
TRDizin 1
Evaluation of Systemic Endothelial Dysfunction in Retinal Vein Occlusions.

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