Propensity score matching analysis of the impact of Syntax score and Syntax score II on new onset atrial fibrillation development in patients with ST segment elevation myocardial infarction
 
Yazarlar (9)
Prof. Dr. İbrahim RENCÜZOĞULLARI Kafkas Üniversitesi, Türkiye
Metin Çağdaş
Kafkas Üniversitesi, Türkiye
Süleyman Karakoyun
Kafkas Üniversitesi, Türkiye
Doç. Dr. İnanç ARTAÇ Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Doğan İLİŞ Kafkas Üniversitesi, Türkiye
Süleyman Çağan Efe
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı ANNALS OF NONINVASIVE ELECTROCARDIOLOGY (Q4)
Dergi ISSN 1082-720X Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 03-2018
Cilt / Sayı / Sayfa 23 / 2 / 12504– DOI 10.1111/anec.12504
Makale Linki http://doi.wiley.com/10.1111/anec.12504
Özet
BackgroundNew‐onset atrial fibrillation (NOAF) is a common complication in the setting of ST segment elevation myocardial infarction (STEMI), and worsened short/long‐term prognosis. Several clinical parameters have already been associated with NOAF development. However, relationship between NOAF and coronary artery disease (CAD) severity in STEMI patients is unclear. This study evaluates the relationship between NOAF and CAD severity using Syntax score (SS) and Syntax score II (SSII) in STEMI patients who were treated with primary percutaneous coronary intervention (pPCI).MethodWe enrolled 1,565 consecutive STEMI patients who were treated with pPCI. Patients with NOAF were compared to patients without NOAF in the entire study population and in a matched population defined by propensity score matching.ResultsPatients with NOAF had significantly higher SS and SSII than those without, both in the matched population (18.6 ± 4 vs 16.75 ± 3.6; p < .001 and 42 ± 13.4 vs 35.1 ± 13.1; p < .001, respectively), and in all study population (18.6 ± 4 vs 16.5 ± 4.6; p < .001 and 42 ± 13.3 vs 31.5 ± 11.9; p < .001 respectively). SSII, compared to its components, was the only independent predictor of NOAF (OR: 1,041 95% CI: 1.015–1.068; p = .002). In the long‐term follow‐up, all‐cause long‐term mortality was significantly higher in patients with NOAF than those without NOAF (23.3% vs. 11%; p = .032).ConclusionThis is the first study to comprehensively examine the relationship between NOAF development and CAD severity using SS and SSII. We demonstrated that, in STEMI patients, high SSII was significantly related to NOAF and was an independent predictor of NOAF. Furthermore, patients with NOAF were associated with poor prognosis.
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