Stereological and Histological Analysis of the Developing Rat Heart
Yazarlar (6)
Muhammed Eyüp Altunkaynak
Ondokuz Mayıs Üniversitesi, Türkiye
Berrin Zühal Altunkaynak
Ondokuz Mayıs Üniversitesi, Türkiye
Deniz Ünal
Atatürk Üniversitesi, Türkiye
Serap Yıldırım
Atatürk Üniversitesi, Türkiye
Bünyami Ünal
Atatürk Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | ANATOMIA HISTOLOGIA EMBRYOLOGIA | ||
| Dergi ISSN | 0340-2096 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2011 |
| Cilt / Sayı / Sayfa | 40 / 6 / 402–410 | DOI | 10.1111/j.1439-0264.2011.01085.x |
| Makale Linki | http://doi.wiley.com/10.1111/j.1439-0264.2011.01085.x | ||
| Özet |
| We studied with quantitative and microscopical methods the heart of rats divided into five age groups: embryos at the age of 11 days, fetuses at the age of 16 days and 20 days and also heart samples of 3-day-old pups and young adults (5 weeks of age) were used (n = 10 samples in each group). At the end of the study; heart samples were obtained from all animals. Stereological estimations were performed on heart volume, volume of heart lumen (ventricles and atria), volume of myocardium, numerical density of the myocyte nuclei and mean nuclear diameter of myocytes. Volumetric values and numerical data were estimated via Cavalieri method and physical dissector, respectively. In this study, histological examination was performed at light and electron microscopic levels. The numerical density of the myocyte nuclei increased from fetuses to young adults. Differences between embryos and fetuses, between fetuses and 3-day-old pups, and between 3-day-old pups and young adults were statistically significant. These results indicate that myogenesis continued in the rat myocardium during prenatal life and after birth. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 6 |