| Yazarlar |
Asuman Orhan Varoğlu
İstanbul Medeniyet Üniversitesi, Türkiye |
|
Mutlu Kuyucu
Türkiye |
|
Recep Demir
Atatürk Üniversitesi, Türkiye |
|
Hamit Acemoğlu
Atatürk Üniversitesi, Türkiye |
Doç. Dr. İsmail CAN
Kafkas Üniversitesi, Türkiye |
|
Fatih Akçay
Atatürk Üniversitesi, Türkiye |
|
Öznur Gürpınar
Türkiye |
|
Fazıl Alper Tekeli
Türkiye |
|
Güllü İştar Dolapçı
Türkiye |
|
Didem Kart
Türkiye |
|
Elmas Ebrü Yalçın
Türkiye |
| Özet |
| Our aim was to evaluate the relationship between lesion volume, serum level of biochemical markers, and clinical situation in ischemic and hemorrhagic stroke. MRI was obtained on 33 ischemic and 28 hemorrhagic strokes. The Cavalieri method was used to measure the volume. To evaluate neurological situation of the patients, we used the National Institutes of Health Stroke Scale (NIHSS) and Rankin Disability Scores at the first, third, seventh, and thirtieth days. We measured the level of leptin, high sensitivity C-reactive protein (hs-CRP), insulin, cortisol, fibrinogen, protein C, protein S, von Willebrand factor, D-dimer, Antitrombin III, and Factor VIII (F VIII) at the same time intervals. In ischemic events, cortisol level at third and seventh days, and fibrinogen level at the first day were correlated with lesion volumes (r = 0.5, p = .02; r = 0.4, p = .02; r = 0.5, p = .005, respectively). In hemorrhagic events, only fibrinogen level was correlated with lesion volumes at third day (r = 0.6, p = .04). No significant differences were found among all these biochemical parameters, neurological situation (p > .05), and lesion volumes at all times. In the prediction of stroke prognosis, lesion volume and all of the evaluated biochemical parameters are not deterministic factors. |
| Anahtar Kelimeler |
| biochemical markers | Cavalieri method | cerebral hemorrhage | cerebral infarct | lesion volume | prognosis |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | INTERNATIONAL JOURNAL OF NEUROSCIENCE |
| Dergi ISSN | 0020-7454 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2009 |
| Cilt No | 119 |
| Sayı | 12 |
| Sayfalar | 2206 / 2218 |
| Doi Numarası | 10.3109/00207450903222733 |
| Makale Linki | http://www.tandfonline.com/doi/full/10.3109/00207450903222733 |
| Atıf Sayıları | |
| WoS | 9 |
