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Anencephalic Fetuses can be an Alternative for Kidney Transplantation a Stereological and Histological Investigation    
Yazarlar
Ahmet Kalaycıoğlu
Karadeniz Teknik Üniversitesi, Türkiye
Mehmet Karaca
Kafkas Üniversitesi, Türkiye
Doç. Dr. İsmail CAN
Kafkas Üniversitesi, Türkiye
Osman Nuri Keleş
Atatürk Üniversitesi, Türkiye
Yılmaz Üçüncü
Recep Tayyip Erdoğan Üniversitesi, Türkiye
Cemal Gündoğdu
Atatürk Üniversitesi, Türkiye
Abdullah Uyanık
Atatürk Üniversitesi, Türkiye
Bünyami Ünal
Atatürk Üniversitesi, Türkiye
Özet
In the study, stereological, histological, and anatomical techniques were used to investigate structural and morphometrical features of anencephalic and normal fetal kidneys. Twenty human fetal kidneys (5 male and 5 female anencephalic fetuses, and 5 male and 5 female normal fetuses) at gestational ages 30 to 35 weeks were examined. Our study used two basic research methods. One was conventional anatomical measurement at the macroscopic level, such as volume, length, weight, etc. The other consisted of conventional and modern microscopic techniques. The microscopic techniques were based on two research methods: histopathological examination at light microscopic level and stereological estimations, including mean kidney volumes, obtained by the Cavalieri method, and the total number and mean height of the glomeruli via the physical dissector method. There was no statistical difference between the two groups in terms of width, height, weight, and fluid replacement volumes. Microscopic quantitative assessment found no statistical differences either, in terms of the kidney volumes and the number and height of the glomeruli. Our findings suggest that kidneys from anencephalic infants may be a suitable alternative for renal transplantation.
Anahtar Kelimeler
Anencephalic donors,Kidney,Stereology,Anatomy,Light Microscopy
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Histology and Histopathology
Dergi ISSN 0213-3911
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce
Basım Tarihi 04-2010
Cilt No 25
Sayı 4
Sayfalar 413 / 422
Doi Numarası 10.14670/HH-25.413