Investigation of serum leptin, ghrelin, irisin, insulin levels and their correlations in cattle with subclinical ketosis
Yazarlar (5)
Doç. Dr. Hale Ergin Eğritağ Burdur Mehmet Akif Ersoy Üniversitesi, Türkiye
Prof. Dr. Oğuz MERHAN Kafkas Üniversitesi, Türkiye
Prof. Dr. Kadir BOZUKLUHAN Kafkas Üniversitesi, Türkiye
Doç. Dr. Kemal Varol Burdur Mehmet Akif Ersoy Üniversitesi, Türkiye
Türker Atcalı Burdur Mehmet Akif Ersoy Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale)
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| Dergi Adı | Mehmet Akif Ersoy Universitesi Veteriner Fakultesi Dergisi | ||
| Dergi ISSN | 2458-9268 | ||
| Dergi Tarandığı Indeksler | TR DİZİN | ||
| Makale Dili | Türkçe | Basım Tarihi | 12-2022 |
| Kabul Tarihi | 26-12-2022 | Yayınlanma Tarihi | 31-12-2022 |
| Cilt / Sayı / Sayfa | 7 / 3 / 223–228 | DOI | 10.24880/maeuvfd.1202455 |
| Makale Linki | http://dx.doi.org/10.24880/maeuvfd.1202455 | ||
| UAK Araştırma Alanları |
Veterinerlik İç Hastalıkları
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| Özet |
| In this study, it was aimed to investigate the correlations with leptin, ghrelin, irisin and insulin levels in the blood serum of cattle with subclinical ketosis. For this purpose, 10 healthy and 10 Holstein cattle with subclinical ketosis obtained from farms in Burdur region were used. A diagnosis of subclinical ketosis was made according to the Rothera test performed in milk, by performing a general clinical examination of the animals. Blood samples were taken from vena jugularis into tubes without anticoagulant. Serum leptin, ghrelin, irisin and insulin levels were measured in the obtained sera using commercial ELISA kits. In cows with subclinical ketosis, serum ghrelin, leptin, irisin and insulin values were increased compared to the control group (p<0.05). In the correlation findings, a highly and quite significant positive correlation was found between serum ghrelin and serum irisin values (r= 0.802; p<0.001). A moderately and quite significant positive correlation was found between plasma ghrelin value and plasma insulin value (r=0.673; p=0.001). A moderately and significant positive correlation was determined between plasma ghrelin value and plasma leptin value, between plasma irisin value and plasma leptin value, and between plasma irisin value and plasma insulin value (r=0.623; p=0.003; r=0.474; p= 0.035; r=0.558; p=0.011). In conclusion, in this study, correlations were observed between serum levels of leptin, irisin, ghrelin and insulin hormones in animals with subclinical ketosis. However, it is thought that leptin, ghrelin, insulin and irisin hormones, which are associated with lipid and carbohydrate metabolism, can be used as important … |
| Anahtar Kelimeler |
| ghrelin | insulin | irisin | ketosis | leptin | negative energy balance |
BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 9 |