Investigation of some acute phase proteins and antioxidant/oxidant system in infected sheep with bluetongue virus disease
  
Yazarlar (5)
Prof. Dr. Oğuz MERHAN Kafkas Üniversitesi, Türkiye
Prof. Dr. Volkan YILMAZ Kafkas Üniversitesi, Türkiye
Prof. Dr. Kadir BOZUKLUHAN Kafkas Üniversitesi, Türkiye
Prof. Dr. Şaban MARAŞLI Kafkas Üniversitesi, Türkiye
Prof. Dr. Metin ÖĞÜN Kafkas Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale)
Dergi Adı Journal of advances in vetbio science and techniques
Dergi ISSN 2548-1150
Dergi Tarandığı Indeksler TR DİZİN
Makale Dili İngilizce Basım Tarihi 09-2022
Cilt / Sayı / Sayfa 7 / 2 / 259–264 DOI 10.31797/vetbio.1063406
Makale Linki www.dergipark.org.tr/vetbio
Özet
In this study, it was aimed to determine the level of some acute phase proteins and oxidative stress in sheep infected with bluetongue virus disease. Twenty five bluetongue virus-infected and 10 healthy sheep were used. Blood samples from V. jugularis of animals were taken into tubes without anticoagulant. Total antioxidant (TAC)/oxidant capacity (TOC), haptoglobin, serum amyloid A (SAA), ceruloplasmin and albumin levels were determined colorimetrically. Oxidative stress index (OSI) was calculated using the formula. As a result of the analysis, when sheep infected with bluetongue virus disease and healthy sheep were compared, it was determined that SAA, TOC and OSI concentrations increased, albumin and TAC values decreased. However haptoglobin and ceruloplasmin levels increased but were statistically insignificant. In conclusion, it was concluded that oxidative stress occurs in sheep infected with bluetongue virus disease and that acute phase proteins haptoglobin, SAA and ceruloplasmin can be used as inflammation markers.
Anahtar Kelimeler
Acute phase proteins | bluetongue virus disease | oxidative stress index (OSI) | sheep