| Yazarlar |
Timor Omar
Türkiye |
Dr. Öğr. Üyesi Muammer KARAKAYALI
Kafkas Üniversitesi, Türkiye |
|
Gökhan Perinçek
Türkiye |
| Özet |
| COVID-19 can cause a variety of cardiac complications and a range of electrocardiographic abnormalities. We analysed cardiological parameters including ECG and high-sensitivity troponin T (hs-TnT) level and their association with mortality in hospitalised patients with COVID-19. We retrospectively analysed the demographics, comorbidities, laboratory findings and electrocardiographic parameters of 453 consecutive patients, whose outcome was clear, died or discharged. Findings were compared between survivors and non-survivors. Also, the same comparison was made between cardiac injury and no-cardiac injury subgroups. The cardiac injury group had significantly higher in-hospital mortality than the no-cardiac injury group. Also, frequencies of atrial fibrillation, axis change, ST-segment/T-wave change, fragmented QRS, premature atrial/ventricular contraction was found to be higher in the cardiac injury group. Moreover, non-survivors had longer QRS intervals, more frequent ST-segment/T-wave changes and isolated S1Q3T3 pattern than surviving patients. Laboratory results showed median values of hs-TnT at the admission of 4.95 ng/L (IQR, 3-12.35) with concentrations markedly higher in the non-surviving patients vs survivors. Hs-TnT value along with age and respiratory rate was found to be an independent predictor of in-hospital mortality in hospitalised patients with COVID-19. Comorbidities were more frequently reported in non-surviving and cardiac injury groups than those surviving and without cardiac injury. In COVID-19 patients, both elevated hs-TnT and ECG abnormalities, suggesting cardiac involvement, on admission portends an ominous prognosis and indicates at higher risk of in-hospital mortality. Prioritised treatment and more aggressive therapeutic strategies could be planned to avoid the occurrence of death in these patients. |
| Anahtar Kelimeler |
| COVID-19 | electrocardiogram | troponin | mortality |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | ACTA CARDIOLOGICA |
| Dergi ISSN | 0001-5385 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 03-2022 |
| Cilt No | 77 |
| Sayı | 3 |
| Sayfalar | 231 / 238 |
| Doi Numarası | 10.1080/00015385.2021.1903704 |
| Makale Linki | http://dx.doi.org/10.1080/00015385.2021.1903704 |
| Atıf Sayıları | |
| WoS | 9 |
| SCOPUS | 7 |
| Google Scholar | 15 |
