| Yazarlar |
Dr. Öğr. Üyesi İnanç ARTAÇ
Kafkas Üniversitesi, Türkiye |
Doç. Dr. Timor OMAR
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Muammer KARAKAYALI
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Doğan İLİŞ
Kafkas Üniversitesi, Türkiye |
Doç. Dr. Yavuz KARABAĞ
Kafkas Üniversitesi, Türkiye |
Prof. Dr. İbrahim RENCÜZOĞULLARI
Kafkas Üniversitesi, Türkiye |
| Özet |
| In recent years, an increasing number of evidences suggests that inflammation plays a significant role in the pathophysiology of pulmonary embolism. Although the association between inflammatory markers and pulmonary embolism prognosis has been previously reported, no studies have investigated the ability of the C-reactive protein/albumin ratio, defined as an inflammation-based prognostic score, to predict death in patients experiencing a pulmonary embolism. This retrospective study included 223 patients experiencing a pulmonary embolism. The study population was divided into two groups according to their C-reactive protein/albumin ratio values and analyzed whether the C-reactive protein/albumin ratio was an independent predictor of late-term mortality. Then, the performance of the C-reactive protein/albumin ratio in predicting patients' outcomes was further compared with its components. Out of 223 patients, death was observed in 57 patients (25.60%) during an average follow-up of 18 months (range: 8-26). The average C-reactive protein/albumin ratio was 0.12 (0.06-0.44). The group with a higher C-reactive protein/albumin ratio was older and had a higher troponin level and simplified Pulmonary Embolism Severity Index score. Independent predictors of late-term mortality were found to be C-reactive protein/albumin ratio (hazard ratio: 1.594, 95% CI: 1.003-2.009; < 0.001), cardiopulmonary disease, simplified Pulmonary Embolism Severity Index score and fibrinolytic therapy. Receiver operating characteristic curve comparisons for both 30-day and late-term mortality demonstrated that the C-reactive protein/albumin ratio was a better predictor than both albumin and C-reactive protein, separately. The present study revealed that the C-reactive protein/albumin ratio is an independent predictor of both 30-day and late-term mortality in patients experiencing a pulmonary embolism. As a marker that can be easily obtained, and calculated, and does not require additional costs C-reactive protein/albumin ratio can be an effective parameter used for prognosis estimation of pulmonary embolism. |
| Anahtar Kelimeler |
| Albumin | c-reactive protein | mortality | pulmonary embolism |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
| Dergi Adı | ASIAN CARDIOVASCULAR & THORACIC ANNALS |
| Dergi ISSN | 0218-4923 |
| Dergi Tarandığı Indeksler | Emerging Sources Citation Index - ESCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 05-2023 |
| Cilt No | 31 |
| Sayı | 4 |
| Sayfalar | 332 / 339 |
| Doi Numarası | 10.1177/02184923231167310 |
| Makale Linki | http://dx.doi.org/10.1177/02184923231167310 |
| Atıf Sayıları | |
| WoS | 2 |
| SCOPUS | 2 |
| Google Scholar | 3 |
