The Prognostic Value of the Systemic Immune-inflammation Index in ST-segment Elevation Myocardial Infarction Patients and Its Correlation with Syntax II Score and TIMI Risk Score
     
Yazarlar (8)
Timor Omar Kafkas Üniversitesi, Türkiye
Burak Akdağ
Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Muammer KARAKAYALI Kafkas Üniversitesi, Türkiye
Doç. Dr. İnanç ARTAÇ Kafkas Üniversitesi, Türkiye
Prof. Dr. Yavuz KARABAĞ Kafkas Üniversitesi, Türkiye
Cihan Dündar
Ankara Bilkent City Hospital, Türkiye
Ayça Arslan Kafkas Üniversitesi, Türkiye
Prof. Dr. İbrahim RENCÜZOĞULLARI Kafkas Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale)
Dergi Adı International Journal of the Cardiovascular Academy
Dergi ISSN 2405-819X Scopus Dergi
Dergi Tarandığı Indeksler Scopus
Makale Dili İngilizce Basım Tarihi 07-2023
Cilt / Sayı / Sayfa 9 / 2 / 36–41 DOI 10.4274/ijca.2023.43043
Makale Linki http://dx.doi.org/10.4274/ijca.2023.43043
Özet
Background and Aim: The systemic immune-inflammation index (SII) has been identified as a novel prognostic marker in various illnesses. We investigated the relationship between SII and mortality in patients undergoing primary percutaneous coronary intervention (pPCI). In addition, we planned to examine how SII correlated with SYNTAX II and thrombolysis in myocardial infarction (TIMI) risk scores in this population. Materials and Methods: This retrospective observational study included patients with ST-segment elevation myocardial infarction who underwent pPCI. The endpoint was 1 year all-cause mortality. SII [(neutrophil x platelet)/lymphocyte] was calculated from admission blood samples. Besides clinical and laboratory findings, SII, Syntax II and TIMI risk scores were compared between survivors and non-survivors. The correlation between SII and Syntax II and TIMI risk scores was also evaluated. Results: The study included 334 patients (82.3% male). In the 1 year follow-up, 18 patients (5.4%) died. The SII, Syntax II, and TIMI risk scores were significantly higher in non-survivors than in survivors [mean (standard deviation: SD), 2423 (2005) vs 1686 (998), P = 0.005; median (interquartile range) 43 (35-53) vs 30 (25-37), P < 0.001; and 4 (2-5) vs 2 (1-3), P = 0.005, respectively]. Furthermore, the Syntax II score, TIMI risk score, and SII was independent predictors of 1 year all-cause mortality. SII showed a significant correlation with Syntax II and TIMI risk scores (R2 = 0.28, P = 0.001 and R2 = 0.37, P < 0.001, respectively). Conclusion: SII might provide additional prognostic data alongside Syntax II and TIMI risk scores in patients undergoing pPCI.
Anahtar Kelimeler
PCI | STEMI | Syntax II score | Systemic immune-inflammation index | TIMI risk score