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The Prognostic Value of the Systemic Immune-inflammation Index in ST-segment Elevation Myocardial Infarction Patients and Its Correlation with Syntax II Score and TIMI Risk Score      
Yazarlar
Doç. Dr. Timor OMAR Doç. Dr. Timor OMAR
Kafkas Üniversitesi, Türkiye
Burak Akdağ
Türkiye
Dr. Öğr. Üyesi Muammer KARAKAYALI Dr. Öğr. Üyesi Muammer KARAKAYALI
Türkiye
Dr. Öğr. Üyesi İnanç ARTAÇ Dr. Öğr. Üyesi İnanç ARTAÇ
Türkiye
Doç. Dr. Yavuz KARABAĞ Doç. Dr. Yavuz KARABAĞ
Türkiye
Cihan Dündar
Türkiye
Dr. Öğr. Üyesi Ayça ARSLAN Dr. Öğr. Üyesi Ayça ARSLAN
Türkiye
Prof. Dr. İbrahim RENCÜZOĞULLARI Prof. Dr. İbrahim RENCÜZOĞULLARI
Türkiye
Özet
Background and Aim: The systemic immune-inflammation index (SII) has been identified as a novel prognostic marker in various illnesses. We investigated the relationship between SII and mortality in patients undergoing primary percutaneous coronary intervention (pPCI). In addition, we planned to examine how SII correlated with SYNTAX II and thrombolysis in myocardial infarction (TIMI) risk scores in this population. Materials and Methods: This retrospective observational study included patients with ST-segment elevation myocardial infarction who underwent pPCI. The endpoint was 1 year all-cause mortality. SII [(neutrophil x platelet)/lymphocyte] was calculated from admission blood samples. Besides clinical and laboratory findings, SII, Syntax II and TIMI risk scores were compared between survivors and non-survivors. The correlation between SII and Syntax II and TIMI risk scores was also evaluated. Results: The study included 334 patients (82.3% male). In the 1 year follow-up, 18 patients (5.4%) died. The SII, Syntax II, and TIMI risk scores were significantly higher in non-survivors than in survivors [mean (standard deviation: SD), 2423 (2005) vs 1686 (998), P = 0.005; median (interquartile range) 43 (35-53) vs 30 (25-37), P < 0.001; and 4 (2-5) vs 2 (1-3), P = 0.005, respectively]. Furthermore, the Syntax II score, TIMI risk score, and SII was independent predictors of 1 year all-cause mortality. SII showed a significant correlation with Syntax II and TIMI risk scores (R2 = 0.28, P = 0.001 and R2 = 0.37, P < 0.001, respectively). Conclusion: SII might provide additional prognostic data alongside Syntax II and TIMI risk scores in patients undergoing pPCI.
Anahtar Kelimeler
PCI | STEMI | Syntax II score | Systemic immune-inflammation index | TIMI risk score
Makale Türü Özgün Makale
Makale Alt Türü Diğer hakemli uluslarası dergilerde yayımlanan tam makale
Dergi Adı Galenos Yayinevi
Dergi ISSN 2405-8181
Dergi Tarandığı Indeksler DOAJ, EBSCO Host
Makale Dili İngilizce
Basım Tarihi 07-2023
Cilt No 9
Sayı 2
Sayfalar 36 / 41
Doi Numarası 10.4274/ijca.2023.43043
Makale Linki http://dx.doi.org/10.4274/ijca.2023.43043