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Relationship Between Fragmented QRS Complex and Long-Term Cardiovascular Outcome in Patients with Essential Hypertension     
Yazarlar
Mehmet Altunova
Türkiye
Hamdi Püşüroğlu
Türkiye
Dr. Öğr. Üyesi Muammer KARAKAYALI
Kafkas Üniversitesi, Türkiye
Ahmet Anıl Şahin
Türkiye
Ali Rıza Demir
Türkiye
Emre Yılmaz
Giresun Üniversitesi, Türkiye
Ahmet Yaşar Çizgici
Türkiye
Mehmet Ertürk
Sağlık Bilimleri Üniversitesi, Türkiye
Özet
Background: In patients with essential hypertension, fragmented QRS has been associated with many remodeling components that might lead to adverse cardiovascular effects. This study aimed to evaluate the relationship between fragmented QRS and adverse events and its potential long-term prognostic value. Methods: The patients with essential hypertension were divided into two groups according to the presence of fragmented QRS: fragmented QRS (+) and fragmented QRS (−). During long-term follow-up, the relationship of fragmented QRS to coronary artery disease, congestive heart failure, stroke, cardiovascular death, all-cause death, and major adverse cardiovascular and cerebrovascular events was evaluated. Results: The study group included 542 patients with essential hypertension. Fragmented QRS on ECG was observed in 224 (41.3%) patients. Considering the incidence rates at the end of 5.6 ± 1.3 years’ follow-up, the total incidence rate of major adverse cardiovascular and cerebrovascular events (P < .001), coronary artery disease (P < .001), and congestive heart failure (P < .001) were higher in patients with fragmented QRS. No significant difference was observed between the two groups in terms of stroke (P=.734), cardiovascular death (P=1), and all-cause death (P=.574). As a result of multiple cox regression analysis, fragmented QRS (P=.005) was identified as an independent predictor for major adverse cardiovascular and cerebrovascular events development. Conclusion: In patients with hypertension, the presence of fragmented QRS was found as an independent predictor for major adverse cardiovascular and cerebrovascular events development.
Anahtar Kelimeler
Essential hypertension,fragmented QRS,major adverse cardiovascular and cerebrovascular events,mortality
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı The Anatolian Journal of Cardiology
Dergi ISSN 2149-2271
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 06-2022
Cilt No 26
Sayı 6
Sayfalar 442 / 449
Doi Numarası 10.5152/AnatolJCardiol.2022.1322
Makale Linki https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361201/pdf/ajc-26-6-442.pdf