| Yazarlar (9) |
Prof. Dr. Haydar YÜKSEK
Kafkas Üniversitesi, Türkiye |
Asıf Berkyürek
Türkiye |
Doç. Dr. Sevda MANAP
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Gül ÖZDEMİR TORAMAN
Kafkas Üniversitesi, Türkiye |
Doç. Dr. Murat BEYTUR
Kafkas Üniversitesi, Türkiye |
|
Havva Balseven
Türkiye |
Prof. Dr. Muzaffer ALKAN
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Fevzi AYTEMİZ
Kafkas Üniversitesi, Türkiye |
|
Özlem Gürsoy Kol
Kafkas Üniversitesi, Türkiye |
| Özet |
| The synthesis of 2-{[3-alkyl(aryl)-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl]azomethine}-phenyl 4-nitrobenzoates 3from the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones 1 with 2-(4-nitrobenzoxy)-benzaldehyde 2is described. The acetylation reactions of the compounds 3 giving compounds 4 have been investigated. The compounds 3 have also been treated with 4-piperidinecarboxamide / piperazine in the presence of formaldehyde according to the Mannich reaction to synthesize 2-{[1-(4-piperidinecarboxamide-1-yl-methyl)-3-alkyl(aryl)-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl]azomethine}-phenyl 4-benzoates 5 and N,N´-bis-{3-alkyl(aryl)-4-[2-(4-nitrobenzoxy)-benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-on-1-yl-methyl}-piperazines 6. The newly synthesized compounds have been characterized using IR, 1H and 13C NMR, UV-Vis and mass spectral data. In addition, the newly synthesized compounds have been screened for their antimicrobial activities. Furthermore, these thirty one new compounds have been analyzed for their in vitro potential antioxidant activities by three different methods. |
| Anahtar Kelimeler |
| 1,2,4-Triazol-5-one | acetylation | antimicrobial activity | antioxidant activity | Mannich base | Schiff base |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Indian Journal of Chemistry |
| Dergi ISSN | 2583-1321 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 06-2022 |
| Cilt No | 61 |
| Sayı | 6 |
| Sayfalar | 623 / 634 |
| Doi Numarası | 10.56042/ijc.v61i6.64214 |
| Makale Linki | http://nopr.niscpr.res.in/bitstream/123456789/60032/1/IJC%2061%286%29%20623-634.pdf |
| Atıf Sayıları | |
| SCOPUS | 2 |
| Google Scholar | 5 |
