| Yazarlar (9) |
H. Yüksek
Kafkas Üniversitesi, Türkiye |
|
A. Berkyürek
Kafkas Üniversitesi, Türkiye |
|
S. Manap
Kafkas Üniversitesi, Türkiye |
|
G. Özdemir
Kafkas Üniversitesi, Türkiye |
Doç. Dr. Murat BEYTUR
Kafkas Üniversitesi, Türkiye |
|
H. Balseven
Kafkas Üniversitesi, Türkiye |
|
M. Alkan
Kafkas Üniversitesi, Türkiye |
|
Faytemiz
Kafkas Üniversitesi, Türkiye |
|
Gürsoy-Kol
Kafkas Üniversitesi, Türkiye |
| Özet |
| The synthesis of 2-{[3-alkyl(aryl)-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl]azomethine}-phenyl 4-nitrobenzoates 3from the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones 1 with 2-(4-nitrobenzoxy)-benzaldehyde 2is described. The acetylation reactions of the compounds 3 giving compounds 4 have been investigated. The compounds 3 have also been treated with 4-piperidinecarboxamide / piperazine in the presence of formaldehyde according to the Mannich reaction to synthesize 2-{[1-(4-piperidinecarboxamide-1-yl-methyl)-3-alkyl(aryl)-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl]azomethine}-phenyl 4-benzoates 5 and N,N´-bis-{3-alkyl(aryl)-4-[2-(4-nitrobenzoxy)-benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-on-1-yl-methyl}-piperazines 6. The newly synthesized compounds have been characterized using IR, 1H and 13C NMR, UV-Vis and mass spectral data. In addition, the newly synthesized compounds have been screened for their antimicrobial activities. Furthermore, these thirty one new compounds have been analyzed for their in vitro potential antioxidant activities by three different methods. |
| Anahtar Kelimeler |
| 1,2,4-Triazol-5-one | acetylation | antimicrobial activity | antioxidant activity | Mannich base | Schiff base |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı |
Indian Journal of Chemistry Ijc
|
| Dergi ISSN | 2583-1321 Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 06-2022 |
| Cilt No | 61 |
| Sayı | 6 |
| Sayfalar | 623 / 634 |
| Doi Numarası | 10.56042/ijc.v61i6.64214 |
| Makale Linki | http://nopr.niscpr.res.in/bitstream/123456789/60032/1/IJC%2061%286%29%20623-634.pdf |
| Atıf Sayıları | |
| SCOPUS | 3 |
| Google Scholar | 7 |
