| Yazarlar (6) |
Prof. Dr. Haydar YÜKSEK
Kafkas Üniversitesi, Türkiye |
Ebru Koca
Türkiye |
Doç. Dr. Murat BEYTUR
Kafkas Üniversitesi, Türkiye |
|
Özlem Gürsoy Kol
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Fevzi AYTEMİZ
Kafkas Üniversitesi, Türkiye |
Prof. Dr. Muzaffer ALKAN
Kafkas Üniversitesi, Türkiye |
| Özet |
| 3-alkyl (aryl)-4-[4-(4-methylbenzoxy) benzylidenamino]-4, 5-dihydro-1H-1, 2, 4-triazol-5-ones (3a, b, d, e, g) reacted with acetic anhydride to afford correspondig 1-acetyl-3-alkyl (aryl)-4-[4-(4-methylbenzoxy) benzylidenamino]-4, 5-dihydro-1H-1, 2, 4-triazol-5-ones (4a, b, d, e, g). The newly synthesized compounds were characterized using by elemental analyses and IR, 1H-NMR, 13C-NMR and UV spectral data. In addition, the synthesized compounds were analyzed for their in vitro potential antioxidant activities in three different methods, including reducing power, free radical scavenging and metal chelating activity. Moreover, antibacterial activity of these five new compounds and eight recently reported 3-alkyl (aryl)-4-[4-(4-methylbenzoxy) benzylidenamino]-4, 5-dihydro-1H-1, 2, 4-triazol-5-ones (3a–h) were screened agaist seven bacteria such as Bacillus subtilis, Yersinia enterocolitca, Bacillus cereus, Staphylococcus aureus, Escherichia coli, Pasterulla multicida and Klebsiella pneumoniae. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale |
| Dergi Adı | Journal of Chemical and Pharmaceutical Research |
| Dergi ISSN | 0975-7384 Scopus Dergi |
| Dergi Tarandığı Indeksler | EBSCO |
| Makale Dili | İngilizce |
| Basım Tarihi | 07-2016 |
| Cilt No | 8 |
| Sayı | 7 |
| Sayfalar | 905 / 911 |
