Synthesis and Antioxidant Properties of Some 3-Alkyl(Aryl)-4-[3-ethoxy-2-(4-toluenesulfonyloxy)-benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-ones
Yazarlar (5)
Prof. Dr. Faruk Kardaş Erzincan Üniversitesi, Türkiye
Doç. Dr. Sevda MANAP Kafkas Üniversitesi, Türkiye
Prof. Dr. Özlem Gürsoy Kol Kafkas Üniversitesi, Türkiye
Doç. Dr. Murat BEYTUR Kafkas Üniversitesi, Türkiye
Prof. Dr. Haydar YÜKSEK Kafkas Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Der Pharma Chemica | ||
| Dergi ISSN | 0975-413X Scopus Dergi | ||
| Dergi Tarandığı Indeksler | Chemical Abstract Services (USA), SCOPUS | ||
| Makale Dili | İngilizce | Basım Tarihi | 11-2016 |
| Cilt / Sayı / Sayfa | 8 / 18 / 274–281 | DOI | – |
| UAK Araştırma Alanları |
Organik Kimya
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| Özet |
| A series of novel 3-alkyl(aryl)-4-[3-ethoxy-2-(4-toluenesulfonyloxy)-benzyliden-amino]-4,5-dihydro-1H-1,2,4- triazol-5-ones (4a-i) were synthesized from the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5- ones (2a-i) with 3-ethoxy-2-(4-toluenesulfonyloxy)-benzaldehyde (3). The new compounds were characterized using by IR, 1H-NMR and 13C-NMR spectral data. In addition, the synthesized compounds were analyzed for their in vitro potential antioxidant activities in three different methods, including reducing power, free radical scavenging and metal chelating activity. These antioxidant activities were compared to those from standard antioxidants, such as EDTA, BHA, BHT and a-tocopherol. |
| Anahtar Kelimeler |
| 4,5-dihydro-1H-1,2,4-triazol-5-one | Antioxidant activity | Schiff base | Syntheses |
