| Yazarlar (7) |
Prof. Dr. Haydar YÜKSEK
Kafkas Üniversitesi, Türkiye |
Osman Kutanis
Türkiye |
|
Gül Özdemir
Türkiye |
Doç. Dr. Murat BEYTUR
Kafkas Üniversitesi, Türkiye |
|
Savaş Kara
Türkiye |
|
Özlem Gürsoy Kol
Kafkas Üniversitesi, Türkiye |
Prof. Dr. Muzaffer ALKAN
Kafkas Üniversitesi, Türkiye |
| Özet |
| In the present study, nine novel 2-methoxy-4-[(3-alkyl/aryl-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl)azonnethine)phenyl 2-methylbenzoates (4a-i) were synthesized from the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2a-i) with 3-(2-methylbenzoxy)-4-methoxybenzaldehyde (3) by using triethylamine. Then, the acetylation reactions of compounds 4a-e and 4g were investigated and 5 type compounds synthesized. The structures of fifteen new compounds were established from IR, H-1 NMR, C-13 NMR, UV and mass spectral data. In addition, the synthesized new 4 and 5 type compounds were analyzed for their in vitro potential antioxidant activities in three different methods; including 1,1-diphhenlyl-2-picrylhydrazyl free radical (DPPH.) scavenging, reducing activity by Fe+3 - Fe+2 transformation and ferrous metal (Fe+2) chelating activities. Furthermore, the synthesized compounds were … |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayınlanan tam makale |
| Dergi Adı | Research Journal of Pharmaceutical, Biological and Chemical Sciences |
| Dergi ISSN | 0975-8585 Scopus Dergi |
| Dergi Tarandığı Indeksler | Emerging Sources Citation Index - ESCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 05-2018 |
| Cilt No | 9 |
| Sayı | 4 |
| Sayfalar | 501 / 512 |
