Yazarlar (7) |
![]() Kafkas Üniversitesi, Türkiye |
![]() Türkiye |
![]() Türkiye |
![]() Kafkas Üniversitesi, Türkiye |
![]() Türkiye |
![]() Kafkas Üniversitesi, Türkiye |
![]() Kafkas Üniversitesi, Türkiye |
Özet |
In the present study, nine novel 2-methoxy-4-[(3-alkyl/aryl-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl)azonnethine)phenyl 2-methylbenzoates (4a-i) were synthesized from the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2a-i) with 3-(2-methylbenzoxy)-4-methoxybenzaldehyde (3) by using triethylamine. Then, the acetylation reactions of compounds 4a-e and 4g were investigated and 5 type compounds synthesized. The structures of fifteen new compounds were established from IR, H-1 NMR, C-13 NMR, UV and mass spectral data. In addition, the synthesized new 4 and 5 type compounds were analyzed for their in vitro potential antioxidant activities in three different methods; including 1,1-diphhenlyl-2-picrylhydrazyl free radical (DPPH.) scavenging, reducing activity by Fe+3 - Fe+2 transformation and ferrous metal (Fe+2) chelating activities. Furthermore, the synthesized compounds were … |
Anahtar Kelimeler |
Makale Türü | Özgün Makale |
Makale Alt Türü | ESCI dergilerinde yayınlanan tam makale |
Dergi Adı | Research Journal of Pharmaceutical, Biological and Chemical Sciences |
Dergi ISSN | 0975-8585 Scopus Dergi |
Dergi Tarandığı Indeksler | Emerging Sources Citation Index - ESCI |
Makale Dili | İngilizce |
Basım Tarihi | 05-2018 |
Cilt No | 9 |
Sayı | 4 |
Sayfalar | 501 / 512 |