| Yazarlar (2) |
Doç. Dr. Murat BEYTUR
Türkiye |
Prof. Dr. Haydar YÜKSEK
Kafkas Üniversitesi, Türkiye |
| Özet |
| 1, 2, 4-TRIAZOLE DERIVATIVES HAVE DRAWN CONSIDERABLE ATTENTION FOR THE PAST FEW DECADES DUE TO THEIR DIVERSE BIOLOGICAL PROPERTIES. MANY 1, 2, 4-TRIAZOLE DERIVATIVES ARE FOUND TO BE POTENT ANTIOXIDANT, ANTI-INFLAMMATORY, ANTIMICROBIAL AND ANTIVIRAL AGENTS. THE IDENTIFICATION OF TRIAZOLES AND DETERMINIATION OF THEIR ANTIOXIDANT ACTIVITIES ARE OF CONSIDERABLE INTEREST BECAUSE OF THE ROLE THEY PLAY IN PHARMACOLOGICAL ACTIONS. IN THIS STUDY, NINE NOVEL 3-ALKYL (ARYL)-4-(4-SINNAMOYLOXYBENZYLIDENAMINO)-4, 5-DIHYDRO-1H-1, 2, 4-TRIAZOL-5-ONES (3) HAVING 4, 5-DIHYDRO-1H-1, 2, 4-TRIAZOL-5-ONE RING WERE SYNTHESIZED FROM THE REACTIONS OF 3-ALKYL (ARYL)-4-AMINO-4, 5-DIHYDRO-1H-1, 2, 4-TRIAZOL-5-ONES (2) WITH 4-SINNAMOYLOXYBENZALDEHYDE AND CHARACTERIZED BY IR, 1H-NMR, 13C-NMR AND UV SPECTRAL DATA. THE STARTING COMPOUNDS 3-ALKYL-4-AMINO-4, 5-DIHYDRO-1H-1, 2, 4-TRIAZOL-5-ONES (2) WERE PREPARED FROM THE REACTIONS OF THE CORRESPONDING ESTER ETHOXYCARBONYLHYDRAZONES WITH AN AQUEOUS SOLUTION OF HYDRAZINE HYDRATE. 4-SINNAMOYLOXYBENZALDEHYDE (1) WAS OBTAINED FROM THE REACTION OF 4-HYDROXYBENZALDEHYDE WITH SINNAMOYL CHLORIDE BY USING TRIETHYLAMINE. IN ADDITION, THE SYNTHESIZED NEW COMPOUNDS WERE ANALYZED FOR THEIR IN VITRO POTENTIAL ANTIOXIDANT ACTIVITIES IN THREE DIFFERENT METHODS, INCLUDING 1, 1 … |
| Anahtar Kelimeler |
| Bildiri Türü | Tebliğ/Bildiri |
| Bildiri Alt Türü | Özet Metin Olarak Yayınlanan Tebliğ (Uluslararası Kongre/Sempozyum) |
| Bildiri Niteliği | Alanında Hakemli Uluslararası Kongre/Sempozyum |
| Bildiri Dili | İngilizce |
| Kongre Adı | The 22nd Iranian Seminar of Organic Chemistry |
| Kongre Tarihi | 19-08-2014 / 21-08-2014 |
| Basıldığı Ülke | İran |
| Basıldığı Şehir | Tabriz |
