| Yazarlar (21) |
Umran Sumeyse Elbahr
Türkiye |
|
Recep Tekin
Türkiye |
|
Milan Papić
Türkiye |
|
Nenad Pandak
Türkiye |
|
Hakan Erdem
Türkiye |
|
Fatma Kesmez Can
Türkiye |
|
Saygın Nayman Alpat
Türkiye |
|
Abdullah Umut Pekok
Türkiye |
|
Filiz Pehlivanoğlu
Türkiye |
Doç. Dr. Murat KARAMEŞE
Kafkas Üniversitesi, Türkiye |
|
Corneliu Petru Popescu
Türkiye |
|
Sholpan Kulzhanova
Türkiye |
|
Selma Tosun
Türkiye |
|
Mustafa Doğan
Türkiye |
|
Teresa Fasciana
Türkiye |
|
Ruxandra Moroti
Türkiye |
|
Ergys Ramosaco
Türkiye |
|
Handan Alay
Türkiye |
|
Edmond Puca
Türkiye |
|
Jurica Arapovic
Türkiye |
|
Natalia Pshenichnaya
Türkiye |
| Özet |
| Although anthrax is a rare zoonotic infection, it still causes significant mortality and morbidity. In this multicenter study, which is the largest anthrax case series ever reported, we aimed to describe the factors leading to dissemination of cutaneous anthrax. Adult patients with cutaneous anthrax from 16 referral centers were pooled. The study had a retrospective design, and included patients treated between January 1, 1990 and December 1, 2019. Probable, and confirmed cases based upon CDC anthrax 2018 case definition were included in the study. A descriptive statistical analysis was performed for all variables. A total of 141 cutaneous anthrax patients were included. Of these, 105 (74%) patients had probable and 36 (26%) had confirmed diagnosis. Anthrax meningitis and bacteremia occurred in three and six patients, respectively. Sequelae were observed in three patients: cicatricial ectropion followed by ocular anthrax (n = 2) and movement restriction on the left hand after surgical intervention (n = 1). One patient had gastrointestinal anthrax. The parameters related to poor outcome (p < 0.05) were fever, anorexia, hypoxia, malaise/fatigue, cellulitis, fasciitis, lymphadenopathy, leukocytosis, high CRP and creatinine levels, longer duration of antimicrobial therapy, and combined therapy. The last two were seemingly the consequences of dissemination rather than being the reasons. The fatality rate was 1.4%. Rapid identification of anthrax is crucial for prompt and effective treatment. Systemic symptoms, disseminated local infection, and high inflammatory markers should alert the treating physicians for the dissemination of the disease. |
| Anahtar Kelimeler |
| Anthrax | Bacteremia | Gastrointestinal | Meningitis | Mortality | Outcome |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
| Dergi Adı | New Microbes and New Infections |
| Dergi ISSN | 2052-2975 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | E-SCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 09-2022 |
| Cilt No | 48 |
| Sayfalar | 101028 / 0 |
| Doi Numarası | 10.1016/j.nmni.2022.101028 |
| Makale Linki | http://dx.doi.org/10.1016/j.nmni.2022.101028 |
| Atıf Sayıları | |
| WoS | 3 |
