Follow-up study of anti-SARS-CoV-2 IgG antibody response in COVID-19 patients up to 6 months after infection
    
Yazarlar (7)
Doç. Dr. Eray ATALAY Kafkas Üniversitesi, Türkiye
Doç. Dr. Murat KARAMEŞE Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Abdullah GÜMÜŞ Kafkas Üniversitesi, Türkiye
Didem Özgür Kafkas Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı FUTURE MICROBIOLOGY (Q3)
Dergi ISSN 1746-0913 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 09-2022
Cilt / Sayı / Sayfa 17 / 13 / 1043–1049 DOI 10.2217/fmb-2022-0006
Makale Linki http://dx.doi.org/10.2217/fmb-2022-0006
Özet
The aim of the current study was to investigate the relationship between lung involvement of SARS-CoV-2 and antibody levels of COVID-19 patients 3 and 6 months from the disease. A total of 156 participants were divided into two groups, Group 1: lung involvement (LI)-positive and Group 2: LI-negative. Biochemical parameters and anti-SARS-CoV-2 IgG antibody levels were measured. The results showed that mean levels of urea, LDH, CRP, ferritin, neutrophil count and D-dimer were significantly higher in the LI-positive group. In addition, mean antibody levels in the 3rd and 6th months were higher in the LI-positive group (p < 0.005). High antibody levels in LI-positive patients correlated with some immunologic and biochemical parameters. Further studies should be performed to determine protective antibody levels against reinfection, how long protective titers last and the mechanisms by which COVID-19 symptoms, demographics and comorbidities may drive higher antibody levels.
Anahtar Kelimeler
antibody response | COVID-19 | follow-up study | SARS-CoV-2