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Follow-up study of anti-SARS-CoV-2 IgG antibody response in COVID-19 patients up to 6 months after infection     
Yazarlar
Doç. Dr. Eray ATALAY
Türkiye
Doç. Dr. Murat KARAMEŞE
Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Abdullah GÜMÜŞ
Kafkas Üniversitesi, Türkiye
İhsan Kahraman
Türkiye
Royça Keleşoğlu
Türkiye
Dr. Öğr. Üyesi Didem ÖZGÜR
Kafkas Üniversitesi, Türkiye
Emin Ediz Tütüncü
Türkiye
Özet
The aim of the current study was to investigate the relationship between lung involvement of SARS-CoV-2 and antibody levels of COVID-19 patients 3 and 6 months from the disease. A total of 156 participants were divided into two groups, Group 1: lung involvement (LI)-positive and Group 2: LI-negative. Biochemical parameters and anti-SARS-CoV-2 IgG antibody levels were measured. The results showed that mean levels of urea, LDH, CRP, ferritin, neutrophil count and D-dimer were significantly higher in the LI-positive group. In addition, mean antibody levels in the 3rd and 6th months were higher in the LI-positive group (p < 0.005). High antibody levels in LI-positive patients correlated with some immunologic and biochemical parameters. Further studies should be performed to determine protective antibody levels against reinfection, how long protective titers last and the mechanisms by which COVID-19 symptoms, demographics and comorbidities may drive higher antibody levels.
Anahtar Kelimeler
antibody response,COVID-19,follow-up study,SARS-CoV-2
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Future Microbiology
Dergi ISSN 1746-0913
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q3
Makale Dili İngilizce
Basım Tarihi 08-2022
Cilt No 17
Sayı 13
Sayfalar 1043 / 1049
Doi Numarası 10.2217/fmb-2022-0006
Makale Linki http://dx.doi.org/10.2217/fmb-2022-0006