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Molecular Characterization, Phylogenetic and Variation Analyzes of SARS-CoV-2 strains in Turkey     
Yazarlar
Doç. Dr. Murat KARAMEŞE
Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Didem ÖZGÜR
Kafkas Üniversitesi, Türkiye
Emin Ediz Tütüncü
Kafkas Üniversitesi, Türkiye
Özet
We present the sequence and single-nucleotide polymorphism (SNP) analysis for 47 complete genomes for SARS-CoV-2 isolates on Turkish patients. The Illumina MiSeq platform was used for sequencing the libraries. The SNPs were detected by using Genome Analysis Toolkit - HaplotypeCaller v.3.8.0 and were inspected on GenomeBrowse v2.1.2. All viral genome sequences of our isolates were located in lineage B under the different clusters, such as B.1 (n = 3), B.1.1 (n = 28) and B.1.9 (n = 16). According to the Global Initiative on Sharing All Influenza Data nomenclature, all of our complete genomes were placed in G, GR and GH clades. In our study, 549 total and 53 unique SNPs were detected. The results indicate that the SARS-CoV-2 sequences of our isolates have great similarity with all Turkish and European sequences.
Anahtar Kelimeler
complete genome sequencing,COVID-19,phylogenetic analysis,SARS-CoV-2,SNP analysis
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Future Microbiology
Dergi ISSN 1746-0913
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q3
Makale Dili İngilizce
Basım Tarihi 09-2021
Doi Numarası 10.2217/fmb-2021-0118
Makale Linki https://www.futuremedicine.com/journal/fmb