Molecular Characterization, Phylogenetic and Variation Analyzes of SARS-CoV-2 strains in Turkey
    
Yazarlar (3)
Doç. Dr. Murat KARAMEŞE Kafkas Üniversitesi, Türkiye
Didem Özgür Kafkas Üniversitesi, Türkiye
Emin Ediz Tütüncü Kafkas Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı FUTURE MICROBIOLOGY (Q3)
Dergi ISSN 1746-0913 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 10-2021
Cilt / Sayı / Sayfa 16 / 15 / 1209–1214 DOI 10.2217/fmb-2021-0118
Makale Linki https://www.futuremedicine.com/journal/fmb
Özet
We present the sequence and single-nucleotide polymorphism (SNP) analysis for 47 complete genomes for SARS-CoV-2 isolates on Turkish patients. The Illumina MiSeq platform was used for sequencing the libraries. The SNPs were detected by using Genome Analysis Toolkit - HaplotypeCaller v.3.8.0 and were inspected on GenomeBrowse v2.1.2. All viral genome sequences of our isolates were located in lineage B under the different clusters, such as B.1 (n = 3), B.1.1 (n = 28) and B.1.9 (n = 16). According to the Global Initiative on Sharing All Influenza Data nomenclature, all of our complete genomes were placed in G, GR and GH clades. In our study, 549 total and 53 unique SNPs were detected. The results indicate that the SARS-CoV-2 sequences of our isolates have great similarity with all Turkish and European sequences.
Anahtar Kelimeler
complete genome sequencing | COVID-19 | phylogenetic analysis | SARS-CoV-2 | SNP analysis