| Yazarlar |
Hüsamettin Aygün
Türkiye |
Murat KARAMEŞE
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Cem ÖZİÇ
Kafkas Üniversitesi, Türkiye |
|
Fikret Uyar
Türkiye |
| Özet |
| Adherent-invasive Escherichia coli (AIEC) pathovar has been identified in intestinal mucosa of patients with Crohn's disease. Our aim was to compare the impact of sterile mucosal media (Muc-M) originated from different parts of the intestine on some pathogenic traits of AIEC LF82 strain. Muc-M composed of certain rates of cell culture medium or M63 minimal medium and mucosal contents obtained from different part of intestine were designed for cell-infection experiments and biofilm-formation assays. The results showed that Muc-M reduced usually pathogenic properties of AIEC LF82. However, LF82 adhesion, invasion and specific biofilm formations were markedly higher in Muc-M than those in Muc-M . In this context, the findings of present study could help the endeavors related to determining molecular targets for AIEC bacteria. |
| Anahtar Kelimeler |
| adhesion | biofilm | Crohn's disease | Escherichia coli LF82 | invasion | pathobiont |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | FUTURE MICROBIOLOGY |
| Dergi ISSN | 1746-0913 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 02-2018 |
| Cilt No | 13 |
| Sayı | 2 |
| Sayfalar | 141 / 149 |
| Doi Numarası | 10.2217/fmb-2017-0133 |
| Makale Linki | https://www.futuremedicine.com/doi/10.2217/fmb-2017-0133 |
| Atıf Sayıları | |
| WoS | 5 |
