The effects of mucosal media on some pathogenic traits of Crohn’s disease-associated Escherichia coli LF82
Yazarlar (4)
Hüsamettin Aygün
Doç. Dr. Murat KARAMEŞE Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Cem ÖZİÇ Kafkas Üniversitesi, Türkiye
Fikret Uyar
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | FUTURE MICROBIOLOGY (Q2) | ||
| Dergi ISSN | 1746-0913 Dergi Bilgileri (2018) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2018 |
| Kabul Tarihi | 22-09-2017 | Yayınlanma Tarihi | 05-01-2018 |
| Cilt / Sayı / Sayfa | 13 / 2 / 141–149 | DOI | 10.2217/fmb-2017-0133 |
| Makale Linki | https://www.futuremedicine.com/doi/10.2217/fmb-2017-0133 | ||
| UAK Araştırma Alanları |
Tıbbi Mikrobiyoloji
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| Özet |
| Adherent-invasive Escherichia coli (AIEC) pathovar has been identified in intestinal mucosa of patients with Crohn's disease. Our aim was to compare the impact of sterile mucosal media (Muc-M) originated from different parts of the intestine on some pathogenic traits of AIEC LF82 strain. Muc-M composed of certain rates of cell culture medium or M63 minimal medium and mucosal contents obtained from different part of intestine were designed for cell-infection experiments and biofilm-formation assays. The results showed that Muc-M reduced usually pathogenic properties of AIEC LF82. However, LF82 adhesion, invasion and specific biofilm formations were markedly higher in Muc-M than those in Muc-M . In this context, the findings of present study could help the endeavors related to determining molecular targets for AIEC bacteria. |
| Anahtar Kelimeler |
| adhesion | biofilm | Crohn's disease | Escherichia coli LF82 | invasion | pathobiont |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 5 |