Investigation of Helicobacter pylori antigen in stool samples of patients with upper gastrointestinal complaints
   
Yazarlar (11)
Zakir Zeki Çalık Türkiye
Doç. Dr. Murat KARAMEŞE Kafkas Üniversitesi, Türkiye
Prof. Dr. Selina AKSAK KARAMEŞE Kafkas Üniversitesi, Türkiye
Yalçın Dicle Muş Alparslan Üniversitesi, Türkiye
Fatih Albayrak Atatürk Üniversitesi, Türkiye
Prof. Dr. Serpil CAN Kafkas Üniversitesi, Türkiye
Bülent Güvendi Türkiye
Alpgiray Turgut Türkiye
Mustafa Çiçek Kahramanmaraş Sütçü İmam Üniversitesi, Türkiye
Halil Yazgı Atatürk Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı BRAZILIAN JOURNAL OF MICROBIOLOGY
Dergi ISSN 1517-8382 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2016
Cilt / Sayı / Sayfa 47 / 1 / 167–171 DOI 10.1016/j.bjm.2015.11.022
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S1517838215000246
Özet
Helicobacter pylori infection is usually acquired in early childhood and it can persist throughout life without antibiotic treatment. This study aimed to compare the accuracy of the noninvasive H. pylori Stool Antigen Test-applied on the stool samples with the invasive gold standart Rapid Urease Test-applied on the gastric biopy samples of patients with upper gastrointestinal complaints. After endoscopy, biopsy and stool specimens were taken in 122 patients. The infection was detected with rapid urease test which is accepted as gold standart test. Rapid, one-step H. pylori card test was applied to all patients stool specimens. In this study 106 of the 122 patients (86.8%) were positive for H. pylori infection, while 16 of the 122 patients (13.2%) were negative. H. pylori card test was negative in 13 of the 16 patients and was positive in 98 of the 106. The sensitivity, specifity, positive and negative predictive values were 92.45%, 81.25%, 97.02%, and 61.90%, respectively. H. pylori card test is rapid, easy, noninvasive and inexpensive methods for detection H. pylori infection. This test showed high sensitivity and specificity. Additionally, it may be a good alternative to invasive tests for the detection of H. pylori infections especially in children.
Anahtar Kelimeler
Helicobacter pylori | Upper gastrointestinal complaints | Rapid urease test | H. pylori card test