The effect of hydrogen-rich water on letrozole-induced polycystic ovary syndrome in rats
 
Yazarlar (6)
Mustafa Makav Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye
Prof. Dr. Mushap KURU Kafkas Üniversitesi, Türkiye
Şükran Yediel Aras Kafkas Üniversitesi, Türkiye
Ebru Karadağ Sarı Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye
Doç. Dr. Menekşe Bulut Iğdır Üniversitesi, Türkiye
Duried Alwazeer
Iğdır Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Reproductive Biomedicine Online (Q1)
Dergi ISSN 1472-6483 Dergi Bilgileri (2023)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 10-2023
Cilt / Sayı / Sayfa 47 / 6 / 103332–0 DOI 10.1016/j.rbmo.2023.103332
Makale Linki https://www.sciencedirect.com/science/article/pii/S1472648323004327?dgcid=coauthor
UAK Araştırma Alanları
Veteriner Doğum ve Jinekolojisi
Özet
Research questionWhat is the effect of hydrogen-rich water on rats with polycystic ovary syndrome (PCOS)?DesignFemale rats were divided into four groups, each consisting of eight animals. The control group received a carboxymethyl cellulose (CMC) solution, the molecular hydrogen (H2) group was given hydrogen-rich water and a CMC solution, the PCOS group was administered letrozole dissolved in a CMC solution and the PCOS + H2 group was given hydrogen-rich water and letrozole dissolved in a CMC solution. Blood and tissue samples were then collected, and biochemical and histopathological analyses were conducted on the samples.ResultsThe histopathological analysis showed a reduction in the number of cysts in the PCOS + H2 group compared with the PCOS group (P < 0.0001). Additionally, the malondialdehyde, cortisol and testosterone data revealed a significant decrease in the PCOS …
Anahtar Kelimeler
glutathione | hydrogen rich water | malondialdehyde | polycystic ovary syndrome | rats
Science Direct
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 13
Scopus 14
Google Scholar 17
The effect of hydrogen-rich water on letrozole-induced polycystic ovary syndrome in rats

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