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Investigation of MUC1 and MUC16 expressions in uterine tissue of Kangal or Kangal cross-bred bitches in prooestrus, metoestrus-dioestrus and anoestrus periods of sexual cycles    
Yazarlar (5)
Buket Bakır
Tekirdağ Namık Kemal Üniversitesi, Türkiye
Hasan Oral
Kafkas Üniversitesi, Türkiye
Prof. Dr. Ebru KARADAĞ SARI Prof. Dr. Ebru KARADAĞ SARI
Kafkas Üniversitesi, Türkiye
Prof. Dr. Mushap KURU Prof. Dr. Mushap KURU
Kafkas Üniversitesi, Türkiye
Hasan Asker
Uşak Üniversitesi, Türkiye
Devamını Göster
Özet
Mucins are glycoprotein molecules found in mucus secretion. They have important functions in the reproductive system such as sperm motility, elimination of bacterial damage and facilitating implantation. In this study, MUC1 and MUC16 expressions in uterine tissues of Kangal or Kangal cross-bred bitchs in proestrus, metoestrus-dioestrus and anoestrus sexual periods were investigated by immunohistochemical method. Uterine tissues of 15 healthy and adopted Kangal or Kangal cross-bred bitches aged 3-6 years were used in the study. The biches were divided into 3 groups according to sexual cycle periods as proestrus (n=5), metaestrus-dioestrus (n=3) and anaestrus (n=7). As a result, MUC1 was found to be expressed in both cornu and corpus uteri epithelial cells, crypt epithelial cells, uterine gland cells, stratum vascularis, myometrium and perimetrium layers in canine uterus. When oestrus cycles were compared, it was found that expression increased more in the metoestrus-dioestrus phase compared to other phases. Expression of MUC16 was observed in the cornu uteri during the metoestrus-dioestrus phase. In this study, MUC1 and MUC16 were determined to be expressed in the uterine tissue of bitches and their release was found to be affected by hormones.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü Diğer hakemli uluslarası dergilerde yayınlanan tam makale
Dergi Adı Caucasian Journal of Science
Dergi ISSN 2148-6840
Dergi Tarandığı Indeksler CiteFactor, Cosmos, Crossref
Makale Dili İngilizce
Basım Tarihi 07-2023
Cilt No 10
Sayı 1
Sayfalar 25 / 37
Doi Numarası 10.48138/cjo.1301466
Makale Linki http://dx.doi.org/10.48138/cjo.1301466