| Yazarlar |
Cemalettin Ayvazoğlu
Türkiye |
Doç. Dr. Enes AKYÜZ
Kafkas Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Ahmet HARMANKAYA
Türkiye |
Dr. Öğr. Üyesi Mert SEZER
Türkiye |
Dr. Öğr. Üyesi Yusuf Umut BATI
Türkiye |
Arş. Gör. Tahir GEZER
Türkiye |
Doç. Dr. Mushap KURU
Türkiye |
| Özet |
| In this study; it was aimed to determine the levels of cardiac biomarkers [cardiac troponin I (cTnI), atri-alnatriureticpeptide (ANP), N-terminal pro-brainnatriureticpeptide (NT-proBNP), homocysteine (HCY), creatineki-nase-myocardialband (CK-MB)] and C-reactive protein (CRP), and the correlations between the semarkers in calves with diarrhea-induced neonatal sepsis, which causes great economic losses, especially genetic material. In the study, 40 neonatal calves with diarrhea-induced neonatal sepsis and 10 clinically healthy neonatal calves aged 0-14 days were used. The study revealed that the serum cTnI, ANP, NT-proBNP, HCY, CK-MB and CRP levels of the calves with neonatal sepsis were statistically significantly higher than those in the control group(P<0.001). The correlation study also showed that there was a high correlation between the cardiac markers here of and the highest correlation was found between ANP and CK-MB (R=0.836**). In conclusion, cTnI, ANP, NT-proBNP, HCY and CK-MB can be suggested as useful prognostic and diagnostic biomarkers of cardiac dysfunctions in calves with suspected sepsis. Furthermore, according to the results of the study; although the suggest that an approximately 10-fold increase in ANP level would be the best marker for early diagnosis of sepsis, ANP may not be an ideal marker due to its short half-life and instability. Therefore, we believe that NT-proBNP, which correlates very significantly with all other markers and increases approximately 7-fold in calves with sepsis, is an important marker in the detection and early diagnosis of sepsis. |
| Anahtar Kelimeler |
| homocysteine | natriuretic peptide | neonatal calves | sepsis | troponin |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Journal Hellenic Veterinary Medical Society |
| Dergi ISSN | 2585-3724 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-2024 |
| Cilt No | 75 |
| Sayı | 1 |
| Sayfalar | 6871 / 6878 |
| Doi Numarası | 10.12681/jhvms.32664 |
| Makale Linki | https://ejournals.epublishing.ekt.gr/index.php/jhvms/article/view/32664/28080 |
| Atıf Sayıları |
