Experimental intravaginal and intrauterine endometritis model: Which model is more useful?
Yazarlar (6)
Doç. Dr. Mustafa MAKAV Kafkas Üniversitesi, Türkiye
Prof. Dr. Mushap KURU Kafkas Üniversitesi, Türkiye
Hatice Beşeren
Kafkas Üniversitesi, Türkiye
Kafkas Üniversitesi, Türkiye
Doç. Dr. Yasemen Adalı İzmir Ekonomi Üniversitesi, Türkiye
Dr. Öğr. Üyesi Mustafa Reha COŞKUN Kafkas Üniversitesi, Türkiye
Doç. Dr. Hüseyin Avni Eroğlu Çanakkale Onsekiz Mart Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale)
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| Dergi Adı | Journal of advances in vetbio science and techniques | ||
| Dergi ISSN | 2548-1150 | ||
| Dergi Tarandığı Indeksler | TR DİZİN | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2022 |
| Kabul Tarihi | 29-12-2022 | Yayınlanma Tarihi | 31-12-2022 |
| Cilt / Sayı / Sayfa | 7 / 3 / 366–375 | DOI | 10.31797/vetbio.1147776 |
| Makale Linki | https://dergipark.org.tr/tr/pub/vetbio/issue/73886 | ||
| UAK Araştırma Alanları |
Sağlık Bilimleri
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| Özet |
| Objectives This study aims to compare the newly created intravaginal endometritis model (IVM) with the intrauterine endometritis model (IUM). Methods E. coli infusion was performed as intravaginally to the IVM and as intrauterinally to the IUM. The lives of all animals were terminated on the 7th day. Histopathological and biochemical analyses (GSH, MDA, Endocan, Endoglin) were performed. Results A significant inflammation was determined in IVM and IUM compared to the control. A significant decrease in GSH and a significant increase in MDA and Endoglin were determined in IVM and IUM compared to the control. There was a statistical increase in the IUM and a numerical increase in the IVM compared to the control. Endometritis was determined by histopathological and biochemical analyses in both IUM and IVM as a result. Conclusion It is predicted in this context that intravaginal administration, which is easier to perform, can be used in experimental studies. |
| Anahtar Kelimeler |
| Endometritis | GSH | MDA | Endocan | Endoglin |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 2 |