Determination of serum paraoxonase activity, total sialic acid concentration, and oxidative status in cattle with clinical mastitis
Yazarlar (5)
H. A. Deveci
Gaziantep Üniversitesi, Türkiye
Gaziantep Üniversitesi, Türkiye
Prof. Dr. Mushap KURU Kafkas Üniversitesi, Türkiye
A. Kükürt
Kafkas Üniversitesi, Türkiye
Kafkas Üniversitesi, Türkiye
M. Makav
Kafkas Üniversitesi, Türkiye
Kafkas Üniversitesi, Türkiye
M. Karapehlivan
Kafkas Üniversitesi, Türkiye
Kafkas Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | International Journal of Veterinary Science | ||
| Dergi ISSN | 2304-3075 Scopus Dergi | ||
| Dergi Tarandığı Indeksler | Scopus | ||
| Makale Dili | İngilizce | Basım Tarihi | 06-2017 |
| Cilt / Sayı / Sayfa | 6 / 3 / 136–140 | DOI | – |
| Makale Linki | http://www.ijvets.com/pdf-files/Volume-6-no-3-2017/136-140.pdf | ||
| Özet |
| The aim of this study is to determine serum paraoxonase activity (PON1), total sialic acid (TSA) concentration, total oxidant (TOS), antioxidant status (TAS), and oxidative stress index (OSI) in cows with clinical mastitis. Fifty Simmental cows, who were 3 and 5 years old and in early lactation period, were used in the study. Blood samples were taken from the groups (Clinical mastitis group, n=30 - Control group, n=20) and serum PON1, TSA concentration, and TOS and TAS levels were determined. PON1 activity, high density lipoprotein (HDL) and TAS levels were found to decrease inversely proportional to inflammation (P<0.001). In addition, TSA, TOS, and OSI levels were detected to increase due to clinical mastitis induced inflammation (P<0.001). In conclusion, it was seen that PON1 activity and TSA concentrations could be used for diagnostic purpose in cows with clinical mastitis. However, we are of the opinion that due to the fact that oxidant status increased but antioxidant status tended to decrease because of inflammation in mastitis, it could be useful to administer antioxidants in addition to treatment for such cases. |
| Anahtar Kelimeler |
| Clinical mastitis | Cow | Oxidative stress | Paraoxonase | Total oxidant and antioxidant status | Total sialic acid |
