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Determination of serum paraoxonase activity, total sialic acid concentration, and oxidative status in cattle with clinical mastitis      
Yazarlar
Haci Ahmet Deveci
Gaziantep Üniversitesi, Türkiye
Doç. Dr. Mushap KURU Doç. Dr. Mushap KURU
Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Abdulsamed KÜKÜRT Dr. Öğr. Üyesi Abdulsamed KÜKÜRT
Kafkas Üniversitesi, Türkiye
Doç. Dr. Mustafa MAKAV Doç. Dr. Mustafa MAKAV
Kafkas Üniversitesi, Türkiye
Prof. Dr. Mahmut KARAPEHLİVAN Prof. Dr. Mahmut KARAPEHLİVAN
Kafkas Üniversitesi, Türkiye
Özet
The aim of this study is to determine serum paraoxonase activity (PON1), total sialic acid (TSA) concentration, total oxidant (TOS), antioxidant status (TAS), and oxidative stress index (OSI) in cows with clinical mastitis. Fifty Simmental cows, who were 3 and 5 years old and in early lactation period, were used in the study. Blood samples were taken from the groups (Clinical mastitis group, n=30 - Control group, n=20) and serum PON1, TSA concentration, and TOS and TAS levels were determined. PON1 activity, high density lipoprotein (HDL) and TAS levels were found to decrease inversely proportional to inflammation (P<0.001). In addition, TSA, TOS, and OSI levels were detected to increase due to clinical mastitis induced inflammation (P<0.001). In conclusion, it was seen that PON1 activity and TSA concentrations could be used for diagnostic purpose in cows with clinical mastitis. However, we are of the opinion that due to the fact that oxidant status increased but antioxidant status tended to decrease because of inflammation in mastitis, it could be useful to administer antioxidants in addition to treatment for such cases.
Anahtar Kelimeler
Clinical mastitis | Cow | Oxidative stress | Paraoxonase | Total oxidant and antioxidant status | Total sialic acid
Makale Türü Özgün Makale
Makale Alt Türü Uluslararası alan indekslerindeki dergilerde yayımlanan tam makale
Dergi Adı International Journal of Veterinary Science
Dergi ISSN 2304-3075
Dergi Tarandığı Indeksler CAB Abstracts, Google Scholar, Veterinary Science Database
Makale Dili İngilizce
Basım Tarihi 06-2017
Cilt No 6
Sayı 3
Sayfalar 136 / 140
Makale Linki http://www.ijvets.com/pdf-files/Volume-6-no-3-2017/136-140.pdf
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
SCOPUS 3
Google Scholar 9

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