Expression of GnRH receptor in the canine corpus luteum, and luteal function following deslorelin acetate-induced puberty delay
Yazarlar (7)
D. Kaya Kafkas Üniversitesi, Veteriner Fakültesi, Türkiye
A. Gram Universität Zürich, İsviçre
M. P. Kowalewski Universität Zürich, İsviçre
S. Schäfer-Somi Artificial Insemination And Embryo Transfer, Avusturya
Prof. Dr. Mushap KURU Kafkas Üniversitesi, Türkiye
A. Boos Universität Zürich, İsviçre
S. Aslan
Near East University, Kıbrıs Rum Kesimi
Near East University, Kıbrıs Rum Kesimi
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Reproduction in Domestic Animals (Q2) | ||
| Dergi ISSN | 0936-6768 Dergi Bilgileri (2017) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2017 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 30-09-2017 |
| Cilt / Sayı / Sayfa | 52 / 6 / 1104–1112 | DOI | 10.1111/rda.13038 |
| Makale Linki | http://doi.wiley.com/10.1111/rda.13038 | ||
| UAK Araştırma Alanları |
Veteriner Doğum ve Jinekolojisi
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| Özet |
| Contents The goals of this study were as follows: (Experiment 1) to examine the basic capability of canine corpora lutea (CL) to respond to GnRH by assessing expression of gonadotropin‐releasing hormone receptor (GnRH‐R) in luteal samples collected throughout the luteal lifespan from non‐pregnant dogs, and (Experiment 2) to investigate the effects of pre‐pubertal application of the GnRH agonist deslorelin acetate on luteal function following the first oestrus. Mature CL were collected during the mid‐luteal phase (days 30–45) from treated and control bitches. Transcript levels of several factors were determined: estrogen receptors (ESR1/ERα, ESR2/ERβ), progesterone (P4)‐receptor (PGR), prolactin receptor (PRLR), PGE2‐synthase (PTGES) and PGE2 receptors (PTGER2/EP2, PTGER4/EP4), vascular endothelial growth factor (VEGFA) and VEGF receptors (VEGFR1 and VEGFR2), cyclooxygenase 2 (COX2 … |
| Anahtar Kelimeler |
| deslorelin | domestic dog (Canis familiaris) | GnRH receptor | luteal function | puberty delay |
