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Olfactory dysfunction in spondyloarthritis     
Yazarlar
Esin Yalçınkaya
Doç. Dr. Mustafa Mert BAŞARAN Doç. Dr. Mustafa Mert BAŞARAN
Ufuk Üniversitesi, Türkiye
Hakan Erdem
Murat Koçyiğit
Türkiye
Aytug Altundag
Thomas Hummel
Özet
Spondyloarthritis (SpA) is a group of disorders characterized by inflammatory arthritis including ankylosing spondylitis, psoriatic arthritis, reactive arthritis and arthritis-related inflammatory bowel diseases. Recently it has been shown that arthritic disorders are accompanied by olfactory dysfunction. We aimed to specifically investigate the association between spondyloarthritis and olfactory impairment. Fifty individuals with SpA and 50 healthy volunteers were included in the study. Olfactory function was evaluated using the "Sniffin' Sticks" test battery. Additionally, effects of age, gender, activity of the disease, HLA-B27 status, medications, and the duration of disease were included in the analysis. SpA patients showed significantly lower scores for odor threshold (T), odor discrimination (D) and odor identification (I) than healthy controls (all p < 0.001). In addition, olfactory loss was negatively correlated with the presence of HLA-B27 (Human Leukocyte Antigen), but not with the current activity of the disease (Bath Ankylosing Spondylitis Activity Index). Neither medication nor duration of the disease had a significant effect on the results. SpA is associated with olfactory loss. Future studies will show whether olfactory function relates to the prognosis of SpA.
Anahtar Kelimeler
Smell | Hyponosmia | Inflammation | Spondyloarthritis | Bechterew
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
Dergi ISSN 0937-4477
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q2
Makale Dili İngilizce
Basım Tarihi 04-2019
Cilt No 276
Sayı 4
Sayfalar 1241 / 1245
Doi Numarası 10.1007/s00405-019-05364-1
Makale Linki http://link.springer.com/10.1007/s00405-019-05364-1
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 4
Olfactory dysfunction in spondyloarthritis

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