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Experimental intravaginal and intrauterine endometritis model: which model is more useful?    
Yazarlar
Doç. Dr. Mustafa MAKAV Doç. Dr. Mustafa MAKAV
Türkiye
Doç. Dr. Mushap KURU Doç. Dr. Mushap KURU
Türkiye
Hatice Beşeren
Türkiye
Yasemen Adalı
Türkiye
Dr. Öğr. Üyesi Mustafa Reha COŞKUN Dr. Öğr. Üyesi Mustafa Reha COŞKUN
Kafkas Üniversitesi, Türkiye
Hüseyin Avni Eroğlu
Türkiye
Özet
This study aims to compare the newly created intravaginal endometritis model (IVM) with the intrauterine endometritis model (IUM). E. coli infusion was used as intravaginally for IVM and intrauterinally for IUM model. The animals were exeuted on the 7th day. Histopathological and biochemical analyses [malondialdehyde (MDA), glutathione (GSH), Endocan, Endoglin] were performed. A significant inflammation was determined in IVM and IUM compared to the control. A significant decrease in GSH and a significant increase in MDA and Endoglin were determined in IVM and IUM compared to the control. There was a statistically significant increase in the IUM and a numerical increase in the IVM compared to the control. Endometritis was determined by histopathological and biochemical analyses in both IUM and IVM model. It is suggested that intravaginal administration, which is easier to perform, can be used in experimental endometritis model studies.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayımlanan tam makale
Dergi Adı Journal of Advances in VetBio Science and Techniques
Dergi ISSN 2548-1150
Dergi Tarandığı Indeksler TR DİZİN
Makale Dili Türkçe
Basım Tarihi 12-2022
Doi Numarası 10.31797/vetbio.1147776
Makale Linki http://dx.doi.org/10.31797/vetbio.1147776
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Experimental intravaginal and intrauterine endometritis model: which model is more useful?

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