Experimental intravaginal and intrauterine endometritis model: which model is more useful?
Yazarlar (6)
Doç. Dr. Mustafa MAKAV
Kafkas Üniversitesi, Türkiye
Prof. Dr. Mushap KURU
Kafkas Üniversitesi, Türkiye
Hatice Beşeren
Kafkas Üniversitesi, Türkiye
Yasemen Adalı
İzmir Ekonomi Üniversitesi, Türkiye
Dr. Öğr. Üyesi Mustafa Reha COŞKUN
Kafkas Üniversitesi, Türkiye
Hüseyin Avni Eroğlu
Çanakkale Onsekiz Mart Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale)
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| Dergi Adı | Journal of advances in vetbio science and techniques | ||
| Dergi ISSN | 2548-1150 | ||
| Dergi Tarandığı Indeksler | TR DİZİN | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2022 |
| Cilt / Sayı / Sayfa | 7 / 3 / 366–375 | DOI | 10.31797/vetbio.1147776 |
| Makale Linki | http://dx.doi.org/10.31797/vetbio.1147776 | ||
| Özet |
| This study aims to compare the newly created intravaginal endometritis model (IVM) with the intrauterine endometritis model (IUM). E. coli infusion was used as intravaginally for IVM and intrauterinally for IUM model. The animals were exeuted on the 7th day. Histopathological and biochemical analyses [malondialdehyde (MDA), glutathione (GSH), Endocan, Endoglin] were performed. A significant inflammation was determined in IVM and IUM compared to the control. A significant decrease in GSH and a significant increase in MDA and Endoglin were determined in IVM and IUM compared to the control. There was a statistically significant increase in the IUM and a numerical increase in the IVM compared to the control. Endometritis was determined by histopathological and biochemical analyses in both IUM and IVM model. It is suggested that intravaginal administration, which is easier to perform, can be used in experimental endometritis model studies. |
| Anahtar Kelimeler |
| Endometritis | GSH | MDA | Endocan | Endoglin |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları |