Yazarlar |
Doç. Dr. Mustafa MAKAV
Türkiye |
Doç. Dr. Mushap KURU
Türkiye |
Hatice Beşeren
Türkiye |
Yasemen Adalı
Türkiye |
Dr. Öğr. Üyesi Mustafa Reha COŞKUN
Kafkas Üniversitesi, Türkiye |
Hüseyin Avni Eroğlu
Türkiye |
Özet |
This study aims to compare the newly created intravaginal endometritis model (IVM) with the intrauterine endometritis model (IUM). E. coli infusion was used as intravaginally for IVM and intrauterinally for IUM model. The animals were exeuted on the 7th day. Histopathological and biochemical analyses [malondialdehyde (MDA), glutathione (GSH), Endocan, Endoglin] were performed. A significant inflammation was determined in IVM and IUM compared to the control. A significant decrease in GSH and a significant increase in MDA and Endoglin were determined in IVM and IUM compared to the control. There was a statistically significant increase in the IUM and a numerical increase in the IVM compared to the control. Endometritis was determined by histopathological and biochemical analyses in both IUM and IVM model. It is suggested that intravaginal administration, which is easier to perform, can be used in experimental endometritis model studies. |
Anahtar Kelimeler |
Makale Türü | Özgün Makale |
Makale Alt Türü | Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayımlanan tam makale |
Dergi Adı | Journal of Advances in VetBio Science and Techniques |
Dergi ISSN | 2548-1150 |
Dergi Tarandığı Indeksler | TR DİZİN |
Makale Dili | Türkçe |
Basım Tarihi | 12-2022 |
Doi Numarası | 10.31797/vetbio.1147776 |
Makale Linki | http://dx.doi.org/10.31797/vetbio.1147776 |