Paraoxonase Activities, Total Sialic Acid Concentration and Lipid Profile After Use of Controlled Internal Drug Release (CIDR) in Gurcu Goats
 
Yazarlar (6)
Prof. Dr. Mushap KURU Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Abdulsamed KÜKÜRT Kafkas Üniversitesi, Türkiye
Doç. Dr. Enes AKYÜZ Kafkas Üniversitesi, Türkiye
Hasan Oral Kafkas Üniversitesi, Türkiye
Recai Kulaksız Balıkesir Üniversitesi, Türkiye
Prof. Dr. Mahmut KARAPEHLİVAN Kafkas Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale)
Dergi Adı International Journal of Veterinary Science
Dergi ISSN 2304-3075 Scopus Dergi
Dergi Tarandığı Indeksler Scopus
Makale Dili İngilizce Basım Tarihi 11-2020
Cilt / Sayı / Sayfa 9 / 4 / 517–522 DOI 10.37422/IJVS/20.068
Makale Linki https://doi.org/10.37422/ijvs/20.068
Özet
The purpose of this study was to determine the effect of the use of controlled internal drug release (CIDR) in Gurcu goats for estrus synchronization on paraoxonase activity (PON1), total sialic acid (TSA) concentration and lipid profile. In the study, 50 Gurcu goats were examined. On day 9, 400 IU pregnant mare serum gonadotropin and 5 mg dinoprost tromethamine were injected. On day 11, CIDR was removed. Following estrus detection, goats on estrus mated with fertility proven Gurcu bucks (mating day). Biochemical analyses were conducted with samples taken on day 0, day 11 and mating day. An increase in TSA concentration and a decrease in PON1 activity was detected according to synchronization days (day 0, day 11, mating day). A decrease was found in total cholesterol (TC), triglycerides and high-density lipoprotein concentrations. On day 11, an increase in TSA concentration and a decrease in PON1 activity was detected compared to control group. According to synchronization days (day 0, day 11, mating day), it was determined that TSA concentration increased in pregnant and non-pregnant goats (P=0.007 and P=0.013, respectively) and PON1 activity decreased (P=0.004). A negative correlation was determined between PON1 and TC (r=-401, P<0.05). In conclusion, CIDR treatment caused changes in PON1 activity, TSA concentration and lipid profile, on the other hand, did not negatively affect fertility.
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