Synthesis, characterization and investigation of antimicrobial and antioxidant activities of some new 2-[(4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl)azomethine]phenyl 4-nitrobenzoate derivatives
Yazarlar (9)
Prof. Dr. Haydar YÜKSEK Kafkas Üniversitesi, Türkiye
Asıf Berkyürek
Doç. Dr. Sevda MANAP Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Gül ÖZDEMİR TORAMAN Kafkas Üniversitesi, Türkiye
Prof. Dr. Murat BEYTUR Kafkas Üniversitesi, Türkiye
Havva Balseven
Prof. Dr. Muzaffer ALKAN Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Fevzi AYTEMİZ Kafkas Üniversitesi, Türkiye
Prof. Dr. Özlem Gürsoy Kol Kafkas Üniversitesi, Türkiye
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Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Indian Journal of Chemistry (Q4) | ||
| Dergi ISSN | 0975-0975 Dergi Bilgileri (2022) | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 06-2022 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 05-07-2022 |
| Cilt / Sayı / Sayfa | 61 / 6 / 623–634 | DOI | 10.56042/ijc.v61i6.64214 |
| Makale Linki | https://doi.org/10.56042/ijc.v61i6.64214 | ||
| UAK Araştırma Alanları |
Organik Kimya
Biyokimya
Spektroskopi
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| Özet |
| The synthesis of 2-{[3-alkyl (aryl)-4, 5-dihydro-1H-1, 2, 4-triazol-5-one-4-yl] azomethine}-phenyl 4-nitrobenzoates 3from the reactions of 3-alkyl (aryl)-4-amino-4, 5-dihydro-1H-1, 2, 4-triazol-5-ones 1 with 2-(4-nitrobenzoxy)-benzaldehyde 2is described. The acetylation reactions of the compounds 3 giving compounds 4 have been investigated. The compounds 3 have also been treated with 4-piperidinecarboxamide/piperazine in the presence of formaldehyde according to the Mannich reaction to synthesize 2-{[1-(4-piperidinecarboxamide-1-yl-methyl)-3-alkyl (aryl)-4, 5-dihydro-1H-1, 2, 4-triazol-5-one-4-yl] azomethine}-phenyl 4-benzoates 5 and N, N-bis-{3-alkyl (aryl)-4-[2-(4-nitrobenzoxy)-benzylidenamino]-4, 5-dihydro-1H-1, 2, 4-triazol-5-on-1-yl-methyl}-piperazines 6. The newly synthesized compounds have been characterized using IR, 1H and 13C NMR, UV-Vis and mass spectral data. In addition, the newly synthesized compounds have been screened for their antimicrobial activities. Furthermore, these thirty one new compounds have been analyzed for their in vitro potential antioxidant activities by three different methods. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 10 |