Synthesis, in vitro Antioxidant and Antimicrobial Activities of Some New 2-(3-Alkyl/Aryl-4,5-dihydro-1H-1,2,4-triazol-5-on-4-yl-azomethine)-phenyl Benzenesulfonate Derivatives
Yazarlar (7)
Prof. Dr. Özlem Gürsoy Kol Kafkas Üniversitesi, Türkiye
Prof. Dr. Haydar YÜKSEK Kafkas Üniversitesi, Türkiye
Gül Özdemir
Doç. Dr. Sevda MANAP Kafkas Üniversitesi, Türkiye
Sezen Buluttekin
Selcan Gökçe
Prof. Dr. Muzaffer ALKAN Kafkas Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of The Chemical Society of Pakistan (Q4)
Dergi ISSN 0253-5106 Dergi Bilgileri (2020)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2020
Cilt / Sayı / Sayfa 42 / 4 / 624–633 DOI 10.52568/000672
UAK Araştırma Alanları
Fen Bilgisi Eğitimi
Özet
Eight new 2-(3-alkyl/aryl-4, 5-dihydro-1H-1, 2, 4-triazol-5-on-4-yl-azomethine) phenyl benzenesulfonates (3) were obtained by the reactions of 3-alkyl (aryl)-4-amino-4, 5-dihydro-1H-1, 2, 4-triazol-5-ones (1) with 2-benzenesulfonyloxybenzaldehyde (2). Moreover, eight N-acetyl derivatives (4) of compounds 3 were obtained. Then, seven new 2-[1-(morpholine-4-yl-methyl)-3-alkyl/aryl-4, 5-dihydro-1H-1, 2, 4-triazol-5-on-4-yl-azomethine) phenyl benzenesulfonates (5) were obtained by the reactions of compounds 3 with formaldehyde and morpholine. The structures of twenty-three newly synthesized compounds were established from infrared, 1H-NMR, 13C-NMR, MS and UV spectral data. In addition, 3, 4 and 5 type compounds were examined for their in vitro potential antioxidant and antibacterial activities. Three different methods were used for the antioxidant assay and the compounds 5 showed a significant activity …
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