Synthesis, in vitro antioxidant and antimicrobial activities of some novel 3-substitued-4-(3-methoxy-4-isobutyryloxybenzylidene-amino)-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives
Yazarlar (4)
Doç. Dr. Sevda MANAP Kafkas Üniversitesi, Türkiye
Prof. Dr. Özlem Gürsoy Kol Kafkas Üniversitesi, Türkiye
Prof. Dr. Muzaffer ALKAN Kafkas Üniversitesi, Türkiye
Prof. Dr. Haydar YÜKSEK Kafkas Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry (Q4) | ||
| Dergi ISSN | 0376-4699 Dergi Bilgileri (2020) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2020 |
| Cilt / Sayı / Sayfa | 59 / 2 / 271–282 | DOI | – |
| Makale Linki | http://nopr.niscair.res.in/handle/123456789/60 | ||
| UAK Araştırma Alanları |
Fen Bilgisi Eğitimi
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| Özet |
| In this study, 3-alkyl(ary1)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones have been reacted with 3-methoxy-4-isobutyryloxybenzaldehyde 2 to afford the corresponding nine new 3-alkyl(ary1)-4-(3-methoxy-4-isobutyryloxybenzylideneamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones 3. Then, the acetylation reactions of compounds 3 have been investigated and 4 type compounds have been obtained. The compounds 3 have also been treated with morpholine/1-methylpiperazine in the presence of formaldehyde according to the Mannich reaction to synthesize 1(morpholine-4-yl-methyl)-3-allcyl(ary1)-4-(3-methoxy-4-i sohutyryloxy-benzylideneamino)-4,5-dihydro-1H-1,2,4-triazol-5ones 5, and 1-(1-methylpiperazin-4-yl-methyl)-3-alkyl(ary1)-4-(3-methoxy-4-isobutyryloxybenzylideneamino)-4,5-dihydro1H-1,2,4-triazol-5-ones 6, respectively. The structures of twenty four new compounds have been characterized by IR, H-1 and … |
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BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 14 |