Synthesis Potentiometric Titrations and Antioxidant Activities os Some 4 Acylamino 4 5 dihydro 1H 1 2 4 triazol 5 one Derivatives
Yazarlar (7)
Prof. Dr. Haydar YÜKSEK Kafkas Üniversitesi, Türkiye
Prof. Dr. Muzaffer ALKAN Kafkas Üniversitesi, Türkiye
Prof. Dr. Fatih İslamoğlu Recep Tayyip Erdoğan Üniversitesi, Türkiye
Prof. Dr. Şule Bahçeci Trabzon Üniversitesi, Türkiye
Prof. Dr. Mahfuz Elmastaş Sağlık Bilimleri Üniversitesi, Türkiye
Prof. Dr. Mustafa Calapoğlu Süleyman Demirel Üniversitesi, Türkiye
Mustafa Özdemir
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Asian Journal of Chem (Q4) | ||
| Dergi ISSN | 0970-7077 Dergi Bilgileri (2008) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2008 |
| Cilt / Sayı / Sayfa | – / 20 / 5311–5321 | DOI | – |
| UAK Araştırma Alanları |
Fen Bilgisi Eğitimi
|
||
| Özet |
| Five novel 3-alkyl-4-cinnamoylamino-4, 5-dihydro-1H-1, 2, 4-triazol-5-ones (2) were synthesized by the reactions of 3-alkyl-4-amino-4, 5-dihydro-1H-1, 2, 4-triazol-5-ones (1) with cinnamoyl chloride and characterized by elemental analyses and IR, 1H NMR, 13C NMR and UV spectral data. The newly synthesized compounds 2 were titrated potentiometrically with tetrabutylammonium hydroxide in four non-aqueous solvents such as isopropyl alcohol, t-butyl alcohol, acetonitrile and N, N-dimethylformamide and the half-neutralization potential values and the corresponding pKa values were determined for all cases. In addition, these new compounds (except compound 2a) and five recently reported 3-alkyl-4-isobutyrylamino-4, 5-dihydro-1H-1, 2, 4-triazol-5-ones (3) were screened for their antioxidant activities. |
| Anahtar Kelimeler |
