Synthesis and Determination of pKa Values of Some New 3 4 Disubstituted 4 5 dihydro 1H 1 2 4 triazol 5 one Derivatives in Non aqueous solvents
Yazarlar (5)
Prof. Dr. Haydar YÜKSEK Kafkas Üniversitesi, Türkiye
Doç. Dr. Zafer OCAK Kafkas Üniversitesi, Türkiye
Prof. Dr. Muzaffer ALKAN Kafkas Üniversitesi, Türkiye
Prof. Dr. Şule Bahçeci Trabzon Üniversitesi, Türkiye
Mustafa Özdemir
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Molecules (Q3) | ||
| Dergi ISSN | 1420-3049 Dergi Bilgileri (2004) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2004 |
| Cilt / Sayı / Sayfa | – / 9 / 232–240 | DOI | – |
| Makale Linki | https://www.mdpi.com/1420-3049/9/4/232 | ||
| UAK Araştırma Alanları |
Fen Bilgisi Eğitimi
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| Özet |
| 3-Alkyl(Aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2) reacted with 2-furoyl chloride and thiophene-2-carbonyl chloride to afford the corresponding 3-alkyl(aryl)-4-(2-furoylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones (3) and 3-alkyl(aryl)-4-(2-thienylcarbonylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones (4), respectively. The new compounds synthesized were characterized by using IR, 1H-NMR, 13C-NMR and UV spectral data together with elemental analysis. In addition, to investigate the effects of solvents and molecular structure upon acidity, compounds 3 and 4 were titrated potentiometrically with tetrabutylammonium hydroxide in four non-aqueous solvents (isopropyl alcohol, tert-butyl alcohol, N,N-dimethylformamide and acetonitrile). The half-neutralization potential values and the corresponding pKa values were determined for all cases. |
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BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 37 |