In vitro anthelmintic efficacy of Haloxylon salicornicum leaves extract using adult Heamonchus contortus worms
Yazarlar (9)
Fatimah A. Al-Saeed
Shameeran Salman Ismael Bamarni
Khalid J. Iqbal
Tauseef Ur Rehman
Ashraf Zaman Faruk
Saira Mahmood
Prof. Dr. Tarkan ŞAHİN Kafkas Üniversitesi, Türkiye
Doç. Dr. Mükremin ÖLMEZ Kafkas Üniversitesi, Türkiye
Dr. Öğr. Üyesi Roshan RIAZ Kafkas Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Pakistan Veterinary Journal (Q1)
Dergi ISSN 2074-7764 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2023
Kabul Tarihi Yayınlanma Tarihi 01-01-2023
Cilt / Sayı / Sayfa 43 / 1 / 91–96 DOI 10.29261/pakvetj/2022.091
Makale Linki http://www.pvj.com.pk/pdf-files/22-425.pdf
UAK Araştırma Alanları
Hayvan Besleme ve Beslenme Hastalıkları
Özet
Herbal dewormers always remained a constant and consistent source of curing various health constraints including parasitic infestations. In this study, anthelmintic efficacy of aqueous methanolic and ethyl acetate extract of Haloxylon (H.) salicornicum was investigated against Heamonchus contortus. Four serial dilutions (25, 12.5, 6.25 and 3.125 mg/mL) were tested to evaluate the highest effective dose of both extracts. Levamisol (0.55 mg/mL) in case of adult motility assay and oxfendazole (25, 12.5 and 6.25 µg/mL) in egg hatch assay were used as standard drugs. After administration of extracts, a highest mean paralysis (10.00±0.00) of all adult worms of H. contortus was exhibited only in 8 and 10 hours post exposure respectively, at highest tested dose of 25 mg/ml. Ethyl acetate and aqueous-methanol extracts were found to inhibit egg hatching up to 91 and 63% respectively, at dose of 25 mg/mL. Hence, the results of current study exhibited a strong anthelmintic potential of H. salicornicum leaves against haemonchosis. Further in vivo studies would be needed to determine the optimal non-lethal dose to maximize the anthelmintic potential of H. salicornicum against this parasite in livestock
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