Hemoglobin‐Inorganic Hybrid Nanoflowers with Different Metal Ions as Potential Oxygen Carrying Systems
Yazarlar (5)
Doç. Dr. Canan GÜLMEZ SAMSA Türkiye
Doç. Dr. Cevahir Altınkaynak Türkiye
Arş. Gör. Merve Türk Türkiye
Prof. Dr. Nalan Özdemir Türkiye
Prof. Dr. Onur ATAKİŞİ Kafkas Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | CHEMISTRY & BIODIVERSITY (Q3) | ||
| Dergi ISSN | 1612-1872 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2022 |
| Kabul Tarihi | 23-11-2021 | Yayınlanma Tarihi | 21-12-2021 |
| Cilt / Sayı / Sayfa | 19 / 1 / 1–9 | DOI | 10.1002/cbdv.202100683 |
| Makale Linki | http://dx.doi.org/10.1002/cbdv.202100683 | ||
| UAK Araştırma Alanları |
Veteriner Biyokimyası
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| Özet |
| Protein‐inorganic hybrid nanoflowers have tremendous potential in bionanotechnology due to their simple method of preparation, high stability and superior properties. Considering these features, the present study was designed to investigate the artificial blood substitution potentials of hemoglobin‐inorganic hybrid nanoflowers. In this context, hemoglobin‐inorganic hybrid nanoflowers (Cu‐NF, Co‐NF and Zn‐NF) were synthesized using with different metal ions (copper, cobalt and zinc), then their oxygen carrying capacity, the hemolytic studies, in vitro oxidant/antioxidant capacity levels and oxidative stress index were reported for the first time. The present findings have revealed that Zn‐NF had significant oxygen content and artificial oxygen carriers (AOC), as well as a significantly low percent hemolysis rate and a safe standard value. Also, hemolysis rate decreased along with the increases in hemoglobin … |
| Anahtar Kelimeler |
| hemoglobin-based hybrid nanoflowers | oxygen carrying ability | hemolytic activity | oxidant | antioxidant capacity |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 12 |
| Google Scholar | 12 |