Investigation the Effect of Boric Acid effect on Antioxidant System, HDL Levels and PON Activity on Rats Feding to the High-Fat Diet
Yazarlar (2)
Dr. Öğr. Üyesi Destan KALAÇAY Kafkas Üniversitesi, Türkiye
Prof. Dr. Onur ATAKİŞİ Kafkas Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(Diğer hakemli uluslarası dergilerde yayınlanan tam makale)
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| Dergi Adı | Caucasian Journal of Science | ||
| Dergi ISSN | 2148-6840 | ||
| Dergi Tarandığı Indeksler | Cite Factor | ||
| Makale Dili | Türkçe | Basım Tarihi | 06-2022 |
| Kabul Tarihi | 21-06-2022 | Yayınlanma Tarihi | 30-06-2022 |
| Cilt / Sayı / Sayfa | 9 / 1 / 49–64 | DOI | 10.48138/cjo.994111 |
| Makale Linki | http://dx.doi.org/10.48138/cjo.994111 | ||
| UAK Araştırma Alanları |
Veteriner Biyokimyası
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| Özet |
| Recent studies have revealed that boron compounds can be effective in the treatment of obesity, which is known to be one of the most dangerous and complex health problems of this age. In this study, the therapeutic effect of boron molecules in the diet on obesity was investigated.For this purpose, the effects of boron compounds on Total Antioxidant Status (TAS), Total Oxidant Status (TOS), High Density Lipoprotein (HDL) levels and paraoxanase (PON) activity were investigated in mice fed a high-fat diet.The study material was 40 Sprague Dawley rats 4-5 months old with a mean live weight of 226.95 ± 5.75 g. Animals were divided into 4 groups as Group I (normal diet), Group II (High fat), Group III (High fat + Boric Acid) and Group IV (Boric Acid). Six weeks after the experiment, blood samples were taken from the animals and TAS, TOS, HDL levels and PON activity were measured from the samples. In addition, the live weight changes of the animals were recorded.At the end of the study, we found that boric acid given in addition to drinking water did not significantly change TAS level and PON activity, but increased TOS and HDL levels. In addition, the weight average of the group treated with boric acid decreased.As a result, boric acid did not have an effect on the antioxidant system, but it caused an increase in HDL level and a decrease in PON activity. In addition, boric acid can be effective in lowering body weight. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 2 |