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Protective effect of L carnitine against oxidative damage caused by experimental chronic aflatoxicosis in quail i Coturnix coturnix i     
Yazarlar (6)
Mehmet Çitil
Kafkas Üniversitesi, Türkiye
Vehbi Güneş
Erciyes Üniversitesi, Türkiye
Prof. Dr. Onur ATAKİŞİ Prof. Dr. Onur ATAKİŞİ
Kafkas Üniversitesi, Türkiye
Ayla Özcan
Kafkas Üniversitesi, Türkiye
Mehmet Tuzcu
Cumhuriyet Üniversitesi, Türkiye
Prof. Dr. Abdullah DOĞAN Prof. Dr. Abdullah DOĞAN
Kafkas Üniversitesi, Türkiye
Devamını Göster
Özet
This study was designed to evaluate the effect of L-carnitine supplementation on the plasma malondialdehyde (MDA) and whole blood reduced glutathione (GSH) concentrations in experimentally-induced chronic aflatoxicosis in quails. For this purpose, a total of 80 quails up to 8 weeks old were divided into four equal groups. Group I served as control, Group II was given L-carnitine at the dose of 200 mg/litre in the drinking water for 60 days, Group III was given 60 microg total aflatoxin/kg diet for 60 days, and Group IV was given both 60 microg total aflatoxin/kg diet and 200 mg L-carnitine/litre in the drinking water for 60 days. Aflatoxin treatment caused a significant increase in plasma MDA and a significant decrease in blood GSH concentrations. On the other hand, there was a significant decrease in plasma MDA and a significant increase in whole blood GSH in the L-carnitine-supplemented group. The present study demonstrated that L-carnitine brought about the inhibition of lipid peroxidation by enhancing antioxidant capacity in quails with chronic aflatoxicosis.
Anahtar Kelimeler
L-carnitine | malondialdehyde | reduced glutathione | aflatoxicosis | quail
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı ACTA VETERINARIA HUNGARICA
Dergi ISSN 0236-6290 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce
Basım Tarihi 08-2005
Cilt No 53
Sayı 3
Sayfalar 319 / 324
Doi Numarası 10.1556/AVet.53.2005.3.5
Makale Linki http://www.akademiai.com/openurl.asp?genre=articleid=doi:10.1556/AVet.53.2005.3.5