ALTERATIONS IN FOLIC ACID VITAMIN B12 THYROID HORMONES AND ANTIOXIDANT OXIDANT LEVELS IN DIFFERENT AGE GROUPS OF SPRAGUE DAWLEY RATS
Yazarlar (2)
Canan Gulmez
Prof. Dr. Onur ATAKİŞİ Kafkas Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | ACTA MEDICA MEDITERRANEA | ||
| Dergi ISSN | 0393-6384 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2016 |
| Cilt / Sayı / Sayfa | 32 / 2 / 361–365 | DOI | 10.19193/0393-6384_2016_2_54 |
| UAK Araştırma Alanları |
Tıbbi Biyokimya
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| Özet |
| Introduction: In the course of time, many structural and functional changes occur at different levels, and they are all known to contribute towards aging. The purpose of the study was to determine the changes in the levels of folic acid, vitamin B12, free T3 and T4, TOS (total oxidant status) and TAS (total antioxidant status) as the rat ages from 6 to 36 months old. Materials and methods: Sprague-Dawley rats were obtained, grown, and divided into five equal groups as follows: Group I (6 months old), Group II (12 months old), Group III (18 months old), Group IV (24 months old) and Group V (36 months old). The levels of folic acid, vitamin B12,free T3 and T4, total oxidant and antioxidant capacity in the blood were analyzed. Results: Folic acid level in Group I was detected to be significantly higher compared to the other groups (P<0.001), and vitamin B12 levels in Group V were determined to be significantly lower than … |
| Anahtar Kelimeler |
| Aging | antioxidant system | folic acid | free T3 and T4 | vitamin B12 |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 1 |