Effects of different nonsteroid antiinflammatory drugs on freetriiodothyronin fT 3 free thyroxin fT 4 and thyroid stimulatinghormone concentration in rabbits
Yazarlar (5)
Erdogan Uzlu
Mehmet Citil
Prof. Dr. Onur ATAKİŞİ Kafkas Üniversitesi, Türkiye
Kuersad Yapar
Hidayet Metin Erdogan
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI
Dergi ISSN 1300-6045 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2007
Cilt / Sayı / Sayfa 13 / 2 / 185–189 DOI 10.5555/20083090227
UAK Araştırma Alanları
Veteriner Biyokimyası
Özet
This study was conducted to investigate the effects of commonly prescribed NSAIDs, flunixin meglumine, carprofen and meloxicam on the concentrations of free triiodothyronine (fT3), free thyroxine (fT4) and thyroid stimulating hormone in healthy rabbits. 32 New Zealand rabbits of similar age and weight and different sex were divided into four equal groups of eight. Rabbits in control group (n=8) received physiologic serum; group FLU (n=8) animals were given flunixin meglumine at dose of 1.1 mg/kg; group CAR (n=8) received 2.2 mg/kg carprofen and group MEL (n=8) was given 0.2 mg/kg meloxicam intramuscularly (IM) for 5 days. Blood samples were collected 4 h after each injection from the vena auricularis into plain vials to determine hormone concentrations. Following separation of serum by centrifugation at 3000 rpm for 10 min, commercially available ELISA kits for free T3, free T3 and TSH were used for …
Anahtar Kelimeler
thyroid hormone concentrations | NSAID | rabbits