Effect of L carnitine on oxidative damage to liver kidney and spleen induced by phenylhydrazine in mice
Yazarlar (5)
A. Ozcan
E. Atakisi
M. Karapehlivan
Prof. Dr. Onur ATAKİŞİ Kafkas Üniversitesi, Türkiye
M. Citil
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı JOURNAL OF APPLIED ANIMAL RESEARCH
Dergi ISSN 0971-2119 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 09-2007
Kabul Tarihi Yayınlanma Tarihi 01-09-2007
Cilt / Sayı / Sayfa 32 / 1 / 97–100 DOI 10.1080/09712119.2007.9706855
Makale Linki http://www.tandfonline.com/doi/abs/10.1080/09712119.2007.9706855
UAK Araştırma Alanları
Veteriner Biyokimyası
Özet
Ozcan, A., Atakisi, E., Karapehlivan, M., Atakisi, O. and Citil, M. 2007. Effect of L-carnitine on oxidative damage to liver, kidney and spleen induced by phenylhydrazine in mice. J. Appl. Anim. Res., 32: 97–100. To investigate the ameliorative effect ofL- carnitine on phenylhydrazine induced oxidative damage to liver, kidney and spleen, twenty-eight Swiss albino mice were divided into four groups and injected 0.9% NaCl (control), 40 mg/kg/day phenylhydrazine, phenylhydrazine+L-carnitine or 1000 mg/kg/day L-carnitine. Malondialdehyde (MDA) level was found to be significantly (P<0.001) lower in phenylhydrazine+L-carnitine group compared to the phenylhydrazine group in all tissues. Reduced kidney glutathione (GSH) level in phenylhydrazine given group was restored to normal by L-carnitine. However, increased uric acid level by phenylhydrazine was not decreased by L-carnitine administration. It appears that …
Anahtar Kelimeler
phenylhydrazine | L-carnitine | mice | reduced glutathione | malondialdehyde | uric acid
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Atıf Sayıları
Web of Science 3
Google Scholar 12
Effect of L carnitine on oxidative damage to liver kidney and spleen induced by phenylhydrazine in mice

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