| Yazarlar |
Levent Ozcan
Türkiye |
|
Emre Can Polat
Türkiye |
Prof. Dr. Ramazan KOCAASLAN
Kafkas Üniversitesi, Türkiye |
|
Efe Önen
Türkiye |
|
Alper Ötünçtemur
Türkiye |
|
Emin Özbek
İstanbul Üniversitesi, Türkiye |
| Özet |
| We aimed to evaluate the efficacy of tadalafil 5 mg once-daily treatment on testosterone levels in patients with erectile dysfunction (ED) accompanied by the metabolic syndrome. A total of 40 men with metabolic syndrome were evaluated for ED in this study. All the patients received 5 mg tadalafil once a day for 3 months. Erectile function was assessed using the five-item version of the International Index of Erectile Function (IIEF) questionnaire. Serum testosterone, follicle-stimulating hormone and luteinising hormone levels were also evaluated, and blood samples were taken between 08.00 and 10.00 in the fasting state. All participants have three or more criteria of metabolic syndrome. At the end of 3 months, mean testosterone values and IIEF scores showed an improvement from baseline values (from 3.6 ± 0.5 to 5.2 ± 0.3, from 11.3 ± 1.9 to 19 ± 0.8 respectively). After the treatment, serum LH levels were decreased (from 5.6 ± 0.6 to 4.6 ± 0.5). There was significantly difference in terms of baseline testosterone and luteinising hormone values and IIEF scores (p < .05). Based on our findings, we recommend tadalafil 5 mg once daily in those men with erectile dysfunction especially low testosterone levels accompanied by metabolic syndrome. |
| Anahtar Kelimeler |
| erectile dysfunction,tadalafil,testosterone |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Andrologia |
| Dergi ISSN | 0303-4569 |
| Dergi Tarandığı Indeksler | SCI |
| Makale Dili | İngilizce |
| Basım Tarihi | 11-2017 |
| Cilt No | 49 |
| Sayı | 9 |
| Sayfalar | 12751 / |
| Doi Numarası | 10.1111/and.12751 |
| Makale Linki | http://doi.wiley.com/10.1111/and.12751 |
| Atıf Sayıları | |
| WoS | 13 |
