The effect of cotinine concentrations in seminal plasma and follicular fluid on the pregnancy outcomes of couples undergoing assisted reproductive techniques
 
Yazarlar (4)
Prof. Dr. Füsun Terzioğlu İstinye Üniversitesi, Türkiye
Prof. Dr. Bensu Karahalil Gazi Üniversitesi, Türkiye
Çiğdem Yücel Hacettepe Üniversitesi, Türkiye
Doç. Dr. Rukiye TÜRK DELİBALTA Kafkas Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı TURKISH JOURNAL OF MEDICAL SCIENCES (Q3)
Dergi ISSN 1300-0144 Dergi Bilgileri (2016)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2016
Kabul Tarihi Yayınlanma Tarihi 01-01-2016
Cilt / Sayı / Sayfa 46 / 5 / 1495–1501 DOI 10.3906/sag-1504-121
Makale Linki http://Journals.tubitak.gov.tr/medical
UAK Araştırma Alanları
Doğum ve Kadın Hastalıkları Hemşireliği
Özet
This study determined the effects of cotinine concentrations in follicular fluid (FF) and seminal plasma (SP) on the pregnancy outcome of couples using assisted reproductive techniques (ARTs). This study was conducted as a case-control study. A total of 217 couples were included in the study. Among these couples, there were nonsmokers (66 women and 40 men), passive smokers (106 women and 54 men), and active smokers (45 women and 123 men). Demographic and smoking data were collected by questionnaire at the onset of treatment. FF and SP samples were obtained from the couples on the day of oocyte retrieval. The cotinine concentrations in the FF and SP of nonsmokers were significantly lower than they were in the other groups (P = 0.001). The difference in cotinine concentrations detected in FF between women with positive pregnancy test results and women with negative pregnancy test results was statistically insignificant. It was also determined that the percentage of clinical pregnancy was lower in nonsmoker women than in passive smoker or smoker women (P > 0.05). Although we found there was no significant difference in the pregnancy outcome between nonsmoker and passive smoker or smoker women, smoking cessation should be an integral part of ARTs.
Anahtar Kelimeler
Infertility | assisted reproductive techniques | seminal plasma | follicular fluid | cigarette | cotinine concentrations