The relationship between adenovirus 36 seropositivity obesity and metabolic profile in Turkish children and adults
Yazarlar (5)
Doç. Dr. Murat KARAMEŞE Kafkas Üniversitesi, Türkiye
Ülkü Altoparlak
Atatürk Üniversitesi, Türkiye
Atatürk Üniversitesi, Türkiye
Turgut Alpgiray
Dr. Öğr. Üyesi Sabiha Aydoğdu Atatürk Üniversitesi, Türkiye
Prof. Dr. Selina AKSAK KARAMEŞE Kafkas Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Epidemiology and Infection | ||
| Dergi ISSN | 0950-2688 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2015 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 16-04-2015 |
| Cilt / Sayı / Sayfa | 143 / 16 / 3550–3556 | DOI | 10.1017/S0950268815000679 |
| Makale Linki | http://www.journals.cambridge.org/abstract_S0950268815000679 | ||
| UAK Araştırma Alanları |
Histoloji ve Embriyoloji
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| Özet |
| SUMMARYObesity potentially arising from viral infection is known as ‘infectobesity’. The latest reports suggest that adenovirus-36 (Adv36) is related to obesity in adults and children. Our aim was not only to determine the Adv36 seropositivity in both obese and non-obese children and adults, but also to investigate correlations between antibody positivity and serum lipid profiles. Both Adv36 positivity and tumour-necrosis-factor-alpha, leptin and interleukin-6 levels were detected in blood samples collected from 146 children and 130 adults by ELISA. Fasting plasma triglycerides, total cholesterol and low-density lipoprotein levels were also measured. Adv36 positivity was determined to be 27·1% and 6% in obese and non-obese children and 17·5% and 4% in obese and non-obese adults, respectively. There was no difference with regard to total cholesterol, low-density lipoprotein, triglyceride, tumour-necrosis-factor-alpha and interleukin-6 levels (P> 0·05). However, there was a significant difference between groups in terms of leptin levels (P< 0·05). We determined the prevalence of Adv36 positivity in obese children and adults. Our results showed that Adv36 may be an obesity agent for both adults and children, parallel with current literature data. However, the available data on a possible relationship between Adv36 infection and obesity both in children and adults do not completely solve the problem. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları |