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Effects of acute kidney injury on clinical outcomes in patients with upper gastrointestinal bleeding   
Yazarlar (8)
Ümit Çakmak
Akdeniz Üniversitesi, Türkiye
Özgür Merhametsiz
Türkiye
Ebru Gök Oğuz
Türkiye
Zafer Ercan
Türkiye
Ayhan Haspulat
Türkiye
Selma Karaahmetoğlu Özkan
Türkiye
Prof. Dr. Başol CANBAKAN Prof. Dr. Başol CANBAKAN
Kafkas Üniversitesi, Türkiye
Mehmet Deniz Aylı
Sağlık Bilimleri Üniversitesi, Türkiye
Devamını Göster
Özet

Aim

Upper gastrointestinal bleeding (UGIB) is a very frequently encountered condition that has a high morbidity and which increases treatment costs. Duration of hospital stay and mortality increases in patients with UGIB complicated by acute kidney injury (AKI). The aim of this study was to reveal risk factors in patients with UGIB developing AKI and to compare clinical outcomes and hospital costs between patients with UGIB developing AKI and those with UGIB not developing AKI.

Material and methods

This retrospective study included 245 patients admitted to the emergency unit and the intensive care unit for internal diseases at Ankara Numune Education and Research Hospital, Turkey.

Results

The difference in mortality rates between the patients with AKI and those without AKI was significant (p < 0.001). The mean duration of intensive care unit stay was 0.2 ± 1.1 days in the patients without AKI (n = 143) and 2.5 ± 5.6 days in the patients with AKI. It was significantly higher in the patients with AKI (p < 0.001). Hospital stay was significantly longer in the patients with AKI than those without AKI, and as severity of AKI increased, hospital stay became considerably longer (p < 0.001). Hospital costs were significantly higher in the patients with AKI than those without AKI, and as severity of AKI increased, hospital costs considerably rose (p < 0.001).

Conclusion

AKI is a condition that lengthens hospital stay, increases hospital costs and creates a burden on health care systems. Detect kidney injury earlier and administering an appropriate treatment can improve clinical outcomes in patients with UGIB developing AKI.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Renal Failure
Dergi ISSN 0886-022X Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 12-2015
Cilt No 38
Sayı 2
Sayfalar 176 / 184
Doi Numarası 10.3109/0886022X.2015.1117923
Makale Linki http://www.tandfonline.com/doi/full/10.3109/0886022X.2015.1117923